Mutants of human insulin-like growth factor I with reduced affinity for the type 1 insulin-like growth factor receptor

Factor I ◽

The Effects of Repeated Daily Recombinant Human Insulin-like Growth Factor I Administration in Adolescents with Type 1 Diabetes

Diabetic Medicine ◽

10.1111/j.1464-5491.1995.tb00391.x ◽

1995 ◽

Vol 12 (10) ◽

pp. 885-892 ◽

Cited By ~ 32

Author(s):

T.D. Cheetham ◽

D.B. Dunger ◽

K. Clayton ◽

J.M.P. Holly ◽

S. Cwyfan-Hughes

Keyword(s):

Type 1 Diabetes ◽

Growth Factor ◽

Human Insulin ◽

Recombinant Human Insulin ◽

Factor I ◽

P03-6 Structural studies of insulin-like growth factor I interacting with the type 1 Insulin-like growth factor receptor in the presence of inhibiting or enhancing monoclonal anti-bodies

Growth Hormone & IGF Research ◽

10.1016/s1096-6374(12)60191-9 ◽

2012 ◽

Vol 22 ◽

pp. S73

Author(s):

D. Thomas ◽

G.K.W. Kong ◽

J.G. Menting ◽

M. Lawrence

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Structural Studies ◽

Factor I ◽

Cotherapy with recombinant human insulin-like growth factor I and insulin improves glycemic control in type 1 diabetes. RhIGF-I in IDDM Study Group

Diabetes Care ◽

10.2337/diacare.22.4.585 ◽

1999 ◽

Vol 22 (4) ◽

pp. 585-592 ◽

Cited By ~ 56

Author(s):

K. M. Thrailkill ◽

T. Quattrin ◽

L. Baker ◽

J. E. Kuntze ◽

P. G. Compton ◽

...

Keyword(s):

Type 1 Diabetes ◽

Growth Factor ◽

Glycemic Control ◽

Human Insulin ◽

Study Group ◽

Recombinant Human Insulin ◽

Factor I ◽

Structural analogs of human insulin-like growth factor I with reduced affinity for serum binding proteins and the type 2 insulin-like growth factor receptor.

10.1016/s0021-9258(18)68777-0 ◽

1988 ◽

Vol 263 (13) ◽

pp. 6233-6239 ◽

Cited By ~ 2

Author(s):

M L Bayne ◽

J Applebaum ◽

G G Chicchi ◽

N S Hayes ◽

B G Green ◽

...

Keyword(s):

Growth Factor ◽

Human Insulin ◽

Binding Proteins ◽

Growth Factor Receptor ◽

Factor I ◽

The roles of tyrosines 24, 31, and 60 in the high affinity binding of insulin-like growth factor-I to the type 1 insulin-like growth factor receptor.

10.1016/s0021-9258(18)55447-8 ◽

1990 ◽

Vol 265 (26) ◽

pp. 15648-15652 ◽

Cited By ~ 17

Author(s):

M.L. Bayne ◽

J. Applebaum ◽

G.G. Chicchi ◽

R.E. Miller ◽

M.A. Cascieri

Keyword(s):

Growth Factor ◽

Growth Factor Receptor ◽

Affinity Binding ◽

High Affinity Binding ◽

Factor I ◽

High Affinity ◽

Canine Tracheal Epithelial Cells Express the Type 1 Insulin-like Growth Factor Receptor and Proliferate in Response to Insulin-like Growth Factor I

American Journal of Respiratory Cell and Molecular Biology ◽

10.1165/ajrcmb/3.3.227 ◽

1990 ◽

Vol 3 (3) ◽

pp. 227-234 ◽

Cited By ~ 8

Author(s):

George Z. Retsch-Bogart ◽

Alan D. Stiles ◽

Billie M. Moats-Staats ◽

Michael R. Van Scott ◽

Richard C. Boucher ◽

...

Keyword(s):

Growth Factor ◽

Epithelial Cells ◽

Growth Factor Receptor ◽

Tracheal Epithelial Cells ◽

Factor I ◽

Tracheal Epithelial ◽

Crystal structure of Drosophila imaginal morphogenesis protein-Late 2 (IMP-L2) in free form and bound to Drosophila insulin-like peptide 5 (DILP5) and human Insulin-like growth factor-I (hIGF1).

Endocrine Abstracts ◽

10.1530/endoabs.35.p337 ◽

2014 ◽

Author(s):

Nikolaj Kulahin ◽

Christopher J. Watson ◽

Waseem Sajid ◽

Gerd Schluckebier ◽

Claus Kristensen ◽

...

Keyword(s):

Crystal Structure ◽

Growth Factor ◽

Human Insulin ◽

Free Form ◽

Factor I ◽

Characterization of a novel alternatively-spliced 5′ exon in the human insulin-like growth factor I (IGF-I) gene, expressed in liver and some cancers

Growth Hormone & IGF Research ◽

10.1016/j.ghir.2019.06.002 ◽

2019 ◽

Vol 46-47 ◽

pp. 36-43

Author(s):

Michael Wallis

Keyword(s):

Growth Factor ◽

Human Insulin ◽

Factor I ◽

Igf I ◽

Alternatively Spliced ◽

Growth Factor I ◽

I Gene

Organization and sequence of the human insulin-like growth factor I gene. Alternative RNA processing produces two insulin-like growth factor I precursor peptides.

10.1016/s0021-9258(19)89179-2 ◽

1986 ◽

Vol 261 (11) ◽

pp. 4828-4832 ◽

Cited By ~ 1

Author(s):

P Rotwein ◽

K M Pollock ◽

D K Didier ◽

G G Krivi

Keyword(s):

Growth Factor ◽

Human Insulin ◽

Rna Processing ◽

Factor I ◽

Growth Factor I ◽

I Gene

The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin.

10.1016/s0021-9258(17)40889-1 ◽

1978 ◽

Vol 253 (8) ◽

pp. 2769-2776 ◽

Cited By ~ 44

Author(s):

E. Rinderknecht ◽

R.E. Humbel

Keyword(s):

Amino Acid ◽

Growth Factor ◽

Amino Acid Sequence ◽

Human Insulin ◽

Structural Homology ◽

Factor I ◽