Determination of Active Concentrations and Association and Dissociation Rate Constants of Interacting Biomolecules:  An Analytical Solution to the Theory for Kinetic and Mass Transport Limitations in Biosensor Technology and Its Experimental Verification†

Kristmundur Sigmundsson; Gísli Másson; Richard Rice; Nicole Beauchemin; Björn Öbrink

doi:10.1021/bi020099h

Determination of Active Concentrations and Association and Dissociation Rate Constants of Interacting Biomolecules: An Analytical Solution to the Theory for Kinetic and Mass Transport Limitations in Biosensor Technology and Its Experimental Verification†

Biochemistry ◽

10.1021/bi020099h ◽

2002 ◽

Vol 41 (26) ◽

pp. 8263-8276 ◽

Cited By ~ 63

Author(s):

Kristmundur Sigmundsson ◽

Gísli Másson ◽

Richard Rice ◽

Nicole Beauchemin ◽

Björn Öbrink

Keyword(s):

Analytical Solution ◽

Mass Transport ◽

Experimental Verification ◽

Rate Constants ◽

Dissociation Rate ◽

Biosensor Technology ◽

Dissociation Rate Constants

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Direct Chromatographic Determination of Dissociation Rate Constants of Ligand−Receptor Complexes: Assessment of the Interaction of Noncompetitive Inhibitors with an Immobilized Nicotinic Acetylcholine Receptor-Based Liquid Chromatography Stationary Phase

Analytical Chemistry ◽

10.1021/ac0504464 ◽

2005 ◽

Vol 77 (16) ◽

pp. 5421-5426 ◽

Cited By ~ 28

Author(s):

Ruin Moaddel ◽

Krzysztof Jozwiak ◽

Rika Yamaguchi ◽

Irving W. Wainer

Keyword(s):

Liquid Chromatography ◽

Nicotinic Acetylcholine Receptor ◽

Rate Constants ◽

Chromatographic Determination ◽

Dissociation Rate ◽

Nicotinic Acetylcholine ◽

Receptor Complexes ◽

Dissociation Rate Constants ◽

Noncompetitive Inhibitors

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Method for Determination of Association and Dissociation Rate Constants of Reversible Bimolecular Reactions by Isothermal Titration Calorimeters

Analytical Chemistry ◽

10.1021/ac062183z ◽

2007 ◽

Vol 79 (7) ◽

pp. 2972-2978 ◽

Cited By ~ 22

Author(s):

Tsuyoshi Egawa ◽

Antonio Tsuneshige ◽

Makoto Suematsu ◽

Takashi Yonetani

Keyword(s):

Rate Constants ◽

Dissociation Rate ◽

Bimolecular Reactions ◽

Dissociation Rate Constants

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Determination of association and dissociation rate constants for bilirubin-bovine serum albumin

Archives of Biochemistry and Biophysics ◽

10.1016/0003-9861(75)90263-5 ◽

1975 ◽

Vol 168 (2) ◽

pp. 351-357 ◽

Cited By ~ 42

Author(s):

Thyge Faerch ◽

Jørgen Jacobsen

Keyword(s):

Bovine Serum Albumin ◽

Serum Albumin ◽

Rate Constants ◽

Bovine Serum ◽

Dissociation Rate ◽

Dissociation Rate Constants

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The elution profile of immobilized liposome chromatography: determination of association and dissociation rate constants

Biochimica et Biophysica Acta (BBA) - Biomembranes ◽

10.1016/j.bbamem.2004.07.007 ◽

2004 ◽

Vol 1665 (1-2) ◽

pp. 167-176 ◽

Cited By ~ 4

Author(s):

Masako Ohno ◽

Tatsuya Ikehara ◽

Toshifumi Nara ◽

Naoki Kamo ◽

Seiji Miyauchi

Keyword(s):

Rate Constants ◽

Dissociation Rate ◽

Elution Profile ◽

Dissociation Rate Constants

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Determination of Formation Constants and Association and Dissociation Rate Constants of Complex Ions by Means of Ion-Transfer Voltammetry.

Analytical Sciences ◽

10.2116/analsci.13.supplement_299 ◽

1997 ◽

Vol 13 (Supplement) ◽

pp. 299-300 ◽

Cited By ~ 3

Author(s):

Hajime Katano ◽

Kotaro Tanaka ◽

Mitsugi Senda

Keyword(s):

Rate Constants ◽

Formation Constants ◽

Dissociation Rate ◽

Ion Transfer ◽

Complex Ions ◽

Dissociation Rate Constants

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Determination of Association and Dissociation Rate Constants in an Inclusion Complex System between Thymol and Sulfated-β-cyclodextrin by Moment Analysis - Affinity Capillary Electrophoresis

Bulletin of the Chemical Society of Japan ◽

10.1246/bcsj.20160193 ◽

2016 ◽

Vol 89 (10) ◽

pp. 1219-1224 ◽

Cited By ~ 9

Author(s):

Kanji Miyabe ◽

Nozomu Suzuki ◽

Youki Shimazaki

Keyword(s):

Complex System ◽

Capillary Electrophoresis ◽

Inclusion Complex ◽

Rate Constants ◽

Dissociation Rate ◽

Moment Analysis ◽

Affinity Capillary Electrophoresis ◽

Dissociation Rate Constants

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A Quantitative1H NMR Method for the Determination of Alkoxyamine Dissociation Rate Constants in Stable Free Radical Polymerization. Application to Styrene Dimer Alkoxyamines

Macromolecules ◽

10.1021/ma061700c ◽

2006 ◽

Vol 39 (26) ◽

pp. 9201-9207 ◽

Cited By ~ 19

Author(s):

Lichun Li ◽

Gordon K. Hamer ◽

Michael K. Georges

Keyword(s):

Free Radical ◽

Radical Polymerization ◽

Rate Constants ◽

Free Radical Polymerization ◽

Dissociation Rate ◽

Stable Free Radical ◽

Nmr Method ◽

Stable Free Radical Polymerization ◽

Dissociation Rate Constants

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Dissociation rate constants and fractional binding of tracer estimated for three antibody populations in unstripped and stripped antiserum

Scandinavian Journal of Clinical and Laboratory Investigation ◽

10.3109/00365517909106096 ◽

1979 ◽

Vol 39 (3) ◽

pp. 215-221 ◽

Cited By ~ 4

Author(s):

V. Kruse

Keyword(s):

Rate Constants ◽

Dissociation Rate ◽

Dissociation Rate Constants

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Faculty Opinions recommendation of Measuring dissociation rate constants of protein complexes through subunit exchange: experimental design and theoretical modeling.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.724167923.793532861 ◽

2017 ◽

Author(s):

Michael Doyle

Keyword(s):

Experimental Design ◽

Rate Constants ◽

Protein Complexes ◽

Dissociation Rate ◽

Theoretical Modeling ◽

Subunit Exchange ◽

Dissociation Rate Constants

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Recombination-dissociation rate constants of acids, determined from polarographic data

Collection of Czechoslovak Chemical Communications ◽

10.1135/cccc19654150 ◽

1965 ◽

Vol 30 (12) ◽

pp. 4150-4167 ◽

Cited By ~ 3

Author(s):

Ya. I. Turyan

Keyword(s):

Rate Constants ◽

Dissociation Rate ◽

Dissociation Rate Constants

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