Functional Characterization of the Heterooligomeric EbrAB Multidrug Efflux Transporter ofBacillus subtilis†

Biochemistry ◽  
2007 ◽  
Vol 46 (17) ◽  
pp. 5218-5225 ◽  
Author(s):  
Zhongge Zhang ◽  
Che Ma ◽  
Owen Pornillos ◽  
Xia Xiu ◽  
Geoffrey Chang ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Efflux Transporter ◽  
Multidrug Efflux ◽  
Ofbacillus Subtilis

Cloning and Functional Characterization of Putative Escherichia coli ABC Multidrug Efflux Transporter YddA

2020 ◽  
Vol 30 (7) ◽  
pp. 982-995
Author(s):  
Zhenyue Feng ◽  
Defu Liu ◽  
Ziwen Liu ◽  
Yimin Liang ◽  
Yanhong Wang ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Functional Characterization ◽  
Efflux Transporter ◽  
Multidrug Efflux

scholarly journals Isolation and functional characterization of CsLsi2, a cucumber silicon efflux transporter gene

2018 ◽  
Vol 122 (4) ◽  
pp. 641-648 ◽  
Author(s):  
Hao Sun ◽  
Yaoke Duan ◽  
Xiaocui Qi ◽  
Liyang Zhang ◽  
Heqiang Huo ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Efflux Transporter ◽  
Transporter Gene

scholarly journals Characterization of the Multiple Transferable Resistance Repressor, MtrR, from Neisseria gonorrhoeae

2005 ◽  
Vol 187 (14) ◽  
pp. 5008-5012 ◽  
Author(s):  
Katherine M. Hoffmann ◽  
Daniel Williams ◽  
William M. Shafer ◽  
Richard G. Brennan
Keyword(s):  
Dna Binding ◽  
Neisseria Gonorrhoeae ◽  
Random Coil ◽  
Efflux Transporter ◽  
Multidrug Efflux ◽  
Sheet Structure ◽  
Β Sheet

ABSTRACT MtrR represses expression of the Neisseria gonorrhoeae mtrCDE multidrug efflux transporter genes. MtrR displays salt-dependent DNA binding, a stoichiometry of two dimers per DNA site, and, for a protein that was expected to be essentially all helical, a high percentage of random coil and possibly β-sheet structure.

Functional characterization of common protein variants in the efflux transporter ABCC11 and identification of T546M as functionally damaging variant

2015 ◽  
Vol 16 (2) ◽  
pp. 193-201 ◽  
Author(s):  
R Arlanov ◽  
T Lang ◽  
G Jedlitschky ◽  
E Schaeffeler ◽  
T Ishikawa ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Efflux Transporter ◽  
Protein Variants

scholarly journals Functional Characterization of Brucella melitensis NorMI, an Efflux Pump Belonging to the Multidrug and Toxic Compound Extrusion Family

2002 ◽  
Vol 46 (9) ◽  
pp. 3050-3053 ◽  
Author(s):  
Martine Braibant ◽  
Laurence Guilloteau ◽  
Michel S. Zygmunt
Keyword(s):  
Vibrio Parahaemolyticus ◽  
Efflux Pump ◽  
Brucella Melitensis ◽  
Functional Characterization ◽  
Multidrug Efflux ◽  
Toxic Compound ◽  
Efflux Mechanism ◽  
M Genome ◽  
Energy Dependent

ABSTRACT Two putative proteins (NorMI and NorMII) similar to the multidrug efflux protein NorM of Vibrio parahaemolyticus are encoded by the Brucella melitensis 16 M genome. We show that a drug-hypersusceptible Escherichia coli strain overexpressing NorMI displays increased resistance to norfloxacin, ciprofloxacin, gentamicin, tetraphenylphosphonium ion, acriflavine, and berberine. This elevated resistance was proven to be mediated by an energy-dependent efflux mechanism. NorMI belongs to the multidrug and toxic compound extrusion family and is the first multidrug efflux protein identified in Brucella spp.

scholarly journals Functional characterization of a novel urate efflux transporter URATv1 ( SLC2A9 ) and its relation to renal hypouricemia.

2009 ◽  
Vol 23 (S1) ◽  
Author(s):  
Promsuk Jutabha ◽  
Naohiko Anzai ◽  
Kimiyoshi Ichida ◽  
Toru Kimura ◽  
Kenichiro Kitamura ◽  
...  
Keyword(s):  
Functional Characterization ◽  
Efflux Transporter ◽  
Renal Hypouricemia
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