Effects of Acetyl CoA on the Pre-Steady-State Kinetics of the Biotin Carboxylation Reaction of Pyruvate Carboxylase†

Biochemistry ◽  
1996 ◽  
Vol 35 (12) ◽  
pp. 3849-3856 ◽  
Author(s):  
Glen B. Legge ◽  
Joy P. Branson ◽  
Paul V. Attwood
Keyword(s):  
Steady State ◽  
Pyruvate Carboxylase ◽  
Acetyl Coa ◽  
Steady State Kinetics ◽  
Kinetics Of

Nonlinear steady-state kinetics of chloramphenicol acetyltransferase

1991 ◽  
Vol 69 (9) ◽  
pp. 630-634
Author(s):  
M. James C. Crabbe ◽  
Derek Goode
Keyword(s):  
Steady State ◽  
Chloramphenicol Acetyltransferase ◽  
Binding Region ◽  
Medium Effects ◽  
Acetyl Coa ◽  
Acetyl Coenzyme A ◽  
Steady State Kinetics ◽  
Steady State Kinetic ◽  
Kinetics Of ◽  
State Kinetic

Steady-state kinetic analysis of chloramphenicol acetyltransferase showed that medium effects (higher temperatures or pH, higher ionic strengths, or lower values for dielectric constant) altered the kinetic behaviour of the enzyme with acetyl-CoA as substrate, but did not significantly affect behaviour with chloramphenicol. This was manifest as an increase in the degree of the rate equation to a 2:2 function. This is interpreted in terms of perturbations to the enzyme at or near the acetyl-CoA binding region of the enzyme.Key words: acetyl coenzyme A, chloramphenicol, antibiotics, enzyme kinetics.

Steady-state kinetics of valproic acid in epileptic patients

1978 ◽  
Vol 24 (3) ◽  
pp. 324-332 ◽  
Author(s):  
J. Bruni ◽  
B. J. Wilder ◽  
L. J. Willmore ◽  
R. J. Perchalski ◽  
H. J. Villarreal
Keyword(s):  
Valproic Acid ◽  
Steady State ◽  
Steady State Kinetics ◽  
Epileptic Patients ◽  
Kinetics Of

Steady-state kinetics of bezafibrate retard in hyperlipidemic geriatric patients

1988 ◽  
Vol 66 (6) ◽  
pp. 250-256 ◽  
Author(s):  
G. Neugebauer ◽  
D. Platt ◽  
T. Vömel ◽  
W. Lösch
Keyword(s):  
Steady State ◽  
Geriatric Patients ◽  
Steady State Kinetics ◽  
Kinetics Of

A DeltaphiH clamp method for analysis of steady-state kinetics of photophosphylation

1990 ◽  
Vol 193 (3) ◽  
pp. 879-886 ◽  
Author(s):  
Heinrich STROTMANN ◽  
Renate THELEN ◽  
Wolfgang MULLER ◽  
Wolfgang BAUM
Keyword(s):  
Steady State ◽  
Steady State Kinetics ◽  
Kinetics Of
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