Essential Thiol Requirement To Restore Pterin- or Substrate-Binding Capability and To Regenerate Native Enzyme-Type High-Spin Heme Spectra in theEscherichia coli-Expressed Tetrahydrobiopterin-Free Oxygenase Domain of Neuronal Nitric Oxide Synthase†

Biochemistry ◽  
1999 ◽  
Vol 38 (48) ◽  
pp. 15853-15862 ◽  
Author(s):  
Masanori Sono ◽  
Amy P. Ledbetter ◽  
Kirk McMillan ◽  
Linda J. Roman ◽  
Thomas M. Shea ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
High Spin ◽  
Substrate Binding ◽  
Neuronal Nitric Oxide Synthase ◽  
Native Enzyme ◽  
Binding Capability ◽  
Oxygenase Domain ◽  
Oxide Synthase

scholarly journals Neuronal nitric oxide synthase generates superoxide from the oxygenase domain

2001 ◽  
Vol 360 (1) ◽  
pp. 247 ◽  
Author(s):  
Hirohito YONEYAMA ◽  
Akira YAMAMOTO ◽  
Hiroaki KOSAKA
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Neuronal Nitric Oxide Synthase ◽  
Oxygenase Domain ◽  
Oxide Synthase

scholarly journals Heme-Dependent Activation of Neuronal Nitric Oxide Synthase by Cytosol Is Due to an Hsp70-Dependent, Thioredoxin-Mediated Thiol–Disulfide Interchange in the Heme/Substrate Binding Cleft

Biochemistry ◽  
2011 ◽  
Vol 50 (33) ◽  
pp. 7146-7156 ◽  
Author(s):  
Yoshihiro Morishima ◽  
Miranda Lau ◽  
Hwei-Ming Peng ◽  
Yoshinari Miyata ◽  
Jason E. Gestwicki ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Nitric Oxide Synthase ◽  
Substrate Binding ◽  
Neuronal Nitric Oxide Synthase ◽  
Binding Cleft ◽  
Oxide Synthase
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