A Molecular Mechanics Method for Predicting the Influence of Ligand Structure on Metal Ion Binding Affinity

1999 ◽  
pp. 102-113 ◽  
Author(s):  
Benjamin P. Hay
Keyword(s):  
Molecular Mechanics ◽  
Binding Affinity ◽  
Metal Ion ◽  
Ion Binding ◽  
Metal Ion Binding ◽  
Molecular Mechanics Method ◽  
Ligand Structure

The engineering of binding affinity at metal ion binding sites for the stabilization of proteins: subtilisin as a test case

Biochemistry ◽  
1988 ◽  
Vol 27 (22) ◽  
pp. 8311-8317 ◽  
Author(s):  
Michael W. Pantoliano ◽  
Marc Whitlow ◽  
Jay F. Wood ◽  
Michele L. Rollence ◽  
Barry C. Finzel ◽  
...  
Keyword(s):  
Binding Affinity ◽  
Binding Sites ◽  
Metal Ion ◽  
Ion Binding ◽  
Test Case ◽  
Metal Ion Binding ◽  
Ion Binding Sites ◽  
Metal Ion Binding Sites

Metal-ion binding affinity of azole-modified oxirane and thiirane resins

1995 ◽  
Vol 27 (1) ◽  
pp. 15-28 ◽  
Author(s):  
P.M. van Berkel ◽  
W.L. Driessen ◽  
J. Reedijk ◽  
D.C. Sherrington ◽  
A. Zitsmanis
Keyword(s):  
Binding Affinity ◽  
Metal Ion ◽  
Ion Binding ◽  
Metal Ion Binding

Photophysical Characterisation, Metal Ion Binding and Enantiomeric Recognition of Chiral Ligands Containing Phenazine Fluorophore

2004 ◽  
Vol 69 (4) ◽  
pp. 885-896 ◽  
Author(s):  
Luisa Stella Dolci ◽  
Péter Huszthy ◽  
Erika Samu ◽  
Marco Montalti ◽  
Luca Prodi ◽  
...  
Keyword(s):  
Metal Ion ◽  
Photophysical Properties ◽  
Ion Binding ◽  
Metal Ion Binding ◽  
Ammonium Ions ◽  
Enantiomerically Pure ◽  
Binding Process ◽  
High Affinity ◽  
Enantiomeric Recognition ◽  
Chiral Species

Enantiomerically pure dimethyl- and diisobutyl-substituted phenazino-18-crown-6 ligands bind metal and ammonium ions and also primary aralkylammonium perchlorates in acetonitrile with high affinity, causing pronounced changes in their luminescence properties. In addition, they show enantioselectivity towards chiral primary aralkylammonium perchlorates. The possibility to monitor the binding process by photoluminescence spectroscopy can gain ground for the design of very efficient enantioselective chemosensors for chiral species. The observed changes in the photophysical properties are also an important tool for understanding the interactions present in the adduct.

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