Inhibitors of Bacterial Transcription Initiation Complex Formation

2013 ◽  
Vol 8 (9) ◽  
pp. 1972-1980 ◽  
Author(s):  
Cong Ma ◽  
Xiao Yang ◽  
Hakan Kandemir ◽  
Marcin Mielczarek ◽  
Elecia B Johnston ◽  
...  
Keyword(s):  
Complex Formation ◽  
Transcription Initiation ◽  
Initiation Complex ◽  
Bacterial Transcription ◽  
Transcription Initiation Complex

Synthesis and biological activity of novel bis-indole inhibitors of bacterial transcription initiation complex formation

2014 ◽  
Vol 12 (18) ◽  
pp. 2882-2894 ◽  
Author(s):  
Marcin Mielczarek ◽  
Ruth V. Devakaram ◽  
Cong Ma ◽  
Xiao Yang ◽  
Hakan Kandemir ◽  
...  
Keyword(s):  
Biological Activity ◽  
Complex Formation ◽  
Transcription Initiation ◽  
Initiation Complex ◽  
Structure Activity Relationships ◽  
Bacterial Transcription ◽  
Structure Activity ◽  
Transcription Initiation Complex

The synthesis of novel bis-indole amides and glyoxylamides as bacterial transcription complex formation inhibitors and their structure–activity relationships are discussed.

scholarly journals Three-dimensional EM structure of an intact activator-dependent transcription initiation complex

2009 ◽  
Vol 106 (47) ◽  
pp. 19830-19835 ◽  
Author(s):  
B. P. Hudson ◽  
J. Quispe ◽  
S. Lara-Gonzalez ◽  
Y. Kim ◽  
H. M. Berman ◽  
...  
Keyword(s):  
Transcription Initiation ◽  
Three Dimensional ◽  
Initiation Complex ◽  
Transcription Initiation Complex
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