Cyclic Polyolefins. XLI. Reaction of Acetyl Bromide and Propionyl Chloride with Cycloöctatetraene

A reaction of 1-cinnamylpiperazine (III) with chloroacetyl gave the chloroacetyl derivative IV which was subjected to substitution reactions with aniline, 4-phenylpiperidin-4-ol (XIa),4-(4-fluorophenyl)piperidin-4-ol (XIb) and 4-(4-chloro-3-trifluoromethyl)piperidin-4-ol and afforded the title compounds V and VII-IX. Acylation reactions of compounds V and VII with propionyl chloride gave the propionanilide derivative VI and the 4-phenyl-4-propanoyloxypiperidine derivative X. With the exception of compound VIII, the new substances are analgetically less active than 1-butyryl-4-cinnamylpiperazine (I) and as antiinflammatory agents they are little active or inactive.

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Photolysis of matrix-isolated acetyl bromide and the infrared spectrum of the 1:1 molecular complex of hydrogen bromide with ketene in solid argon

Journal of Molecular Structure ◽

10.1016/0022-2860(93)80286-5 ◽

1993 ◽

Vol 299 ◽

pp. 105-109 ◽

Cited By ~ 4

Author(s):

N. Kogure ◽

R. Hatakeyama ◽

E. Suzuki ◽

F. Watari

Keyword(s):

Infrared Spectrum ◽

Molecular Complex ◽

Hydrogen Bromide ◽

Acetyl Bromide ◽

Solid Argon

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Reactions of Lignin Model ß-Aryl Ethers with Acetyl Bromide

Holzforschung ◽

10.1515/hfsg.1996.50.4.360 ◽

1996 ◽

Vol 50 (4) ◽

pp. 360-364 ◽

Cited By ~ 9

Author(s):

Fachuang Lu ◽

John Ralph

Keyword(s):

Acetyl Bromide ◽

Lignin Model ◽

Aryl Ethers

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Acetyl Bromide-Alcohols as Convenient Reaction Systems for: a) Removal ofN-tert-Boc,N-Cbz AndN-Ac Protective Groups, b) Esterifications and Transesterifications, c) Debenzylation of Aryl-O-Benzyl Ethers

Synthetic Communications ◽

10.1080/00397919908086117 ◽

1999 ◽

Vol 29 (8) ◽

pp. 1405-1408 ◽

Cited By ~ 7

Author(s):

Anat Lesk And ◽

Abraham Nudelman

Keyword(s):

Acetyl Bromide ◽

Reaction Systems ◽

Protective Groups ◽

Benzyl Ethers

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Microwave spectrum of propionyl chloride

Journal of Molecular Structure ◽

10.1016/0022-2860(76)85086-7 ◽

1976 ◽

Vol 33 (2) ◽

pp. 227-237 ◽

Cited By ~ 20

Author(s):

H. Karlsson

Keyword(s):

Microwave Spectrum ◽

Propionyl Chloride

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HALIDE ALKOXIDES OF SAMARIUM: III. REACTIONS OF SAMARIUM ALKOXIDES WITH ACETYL CHLORIDE AND ACETYL BROMIDE

Canadian Journal of Chemistry ◽

10.1139/v66-322 ◽

1966 ◽

Vol 44 (18) ◽

pp. 2131-2137 ◽

Cited By ~ 5

Author(s):

B. S. Sankhla ◽

R. N. Kapoor

Keyword(s):

Hydrogen Chloride ◽

Acetyl Chloride ◽

Acetyl Bromide ◽

Acyl Halide ◽

Exothermic Reactions ◽

Stoichiometric Ratios ◽

Derivatives Of ◽

Acyl Halides

The reactions of samarium n-butoxide, isopropoxide, and tert-butoxide with acyl halides in different stoichiometric ratios have been studied and products of the type Sm(OR)2X, Sm(OR)X2•0.5CH3COOR and SmX3•CH3COOR (where R = C4H9n, C3H7i, or C4H9t and X = Cl or Br) have been isolated in quantitative yields. All these reactions are exothermic and the amount of heat liberated also increases with the increase in the concentration of acyl halide. These reactions have been further confirmed by the reactions with anhydrous samarium trichloride and the corresponding esters, which are also exothermic reactions. Attempts to sublime the dialkoxy monohalide derivatives of samarium were unsuccessful. The reaction of a dry current of hydrogen chloride gas on samarium isopropoxide has also been investigated.

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