X-ray Absorption and Resonance Raman Studies of Methyl-Coenzyme M Reductase Indicating That Ligand Exchange and Macrocycle Reduction Accompany Reductive Activation†

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Qun Tang ◽  
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Yih-Chern Horng ◽  
Michael J. Maroney ◽  
Stephen W. Ragsdale ◽  
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Marwah Madkhali ◽  
Conor Douglas Rankine ◽  
Thomas James Penfold

Many chemical and biological reactions, including ligand exchange processes, require thermal energy for the reactants to overcome a transition barrier and reach the product state. Temperature-jump (T-jump) spectroscopy uses a...


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