Development of Long-Acting Dopamine Transporter Ligands as Potential Cocaine-Abuse Therapeutic Agents:  Chiral Hydroxyl-Containing Derivatives of 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine

2002 ◽  
Vol 45 (6) ◽  
pp. 1321-1329 ◽  
Author(s):  
Ling-Wei Hsin ◽  
Christina M. Dersch ◽  
Michael H. Baumann ◽  
David Stafford ◽  
John R. Glowa ◽  
...  
ChemInform ◽  
2003 ◽  
Vol 34 (21) ◽  
Author(s):  
Ling-Wei Hsin ◽  
Thomas Prisinzano ◽  
Chavon R. Wilkerson ◽  
Christina M. Dersch ◽  
Robert Horel ◽  
...  

2003 ◽  
Vol 13 (3) ◽  
pp. 553-556 ◽  
Author(s):  
Ling-Wei Hsin ◽  
Thomas Prisinzano ◽  
Chavon R Wilkerson ◽  
Christina M Dersch ◽  
Robert Horel ◽  
...  

2003 ◽  
Vol 46 (13) ◽  
pp. 2589-2598 ◽  
Author(s):  
Jianjing Cao ◽  
Santosh S. Kulkarni ◽  
Stephen M. Husbands ◽  
Wayne D. Bowen ◽  
Wanda Williams ◽  
...  

2020 ◽  
Vol 27 (40) ◽  
pp. 6864-6887 ◽  
Author(s):  
Mohd Adil Shareef ◽  
Irfan Khan ◽  
Bathini Nagendra Babu ◽  
Ahmed Kamal

Background:: Imidazo[2,1-b]thiazole, a well-known fused five-membered hetrocycle is one of the most promising and versatile moieties in the area of medicinal chemistry. Derivatives of imidazo[2,1-b]thiazole have been investigated for the development of new derivatives that exhibit diverse pharmacological activities. This fused heterocycle is also a part of a number of therapeutic agents. Objective:: To review the extensive pharmacological activities of imidazo[2,1-b]thiazole derivatives and the new molecules developed between 2000-2018 and their usefulness. Method:: Thorough literature review of all relevant papers and patents was conducted. Conclusion:: The present review, covering a number of aspects, is expected to provide useful insights in the design of imidazo[2,1-b]thiazole-based compounds and would inspire the medicinal chemists for a comprehensive and target-oriented information to achieve a major breakthrough in the development of clinically viable candidates.


2011 ◽  
Vol 21 (11) ◽  
pp. 3457-3461 ◽  
Author(s):  
Maria Prat ◽  
María Antonia Buil ◽  
Maria Dolors Fernández ◽  
Jordi Castro ◽  
Juan Manuel Monleón ◽  
...  

2014 ◽  
Vol 349 (2) ◽  
pp. 297-309 ◽  
Author(s):  
Takato Hiranita ◽  
Derek S. Wilkinson ◽  
Weimin C. Hong ◽  
Mu-Fa Zou ◽  
Theresa A. Kopajtic ◽  
...  

2006 ◽  
Vol 8 (1) ◽  
pp. E196-E203 ◽  
Author(s):  
F. Ivy Carroll ◽  
James L. Howard ◽  
Leonard L. Howell ◽  
Barbara S. Fox ◽  
Michael J. Kuhar

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