Design, Synthesis, and Antiproliferative Activity of Some New Pyrazole-Fused Amino Derivatives of the Pyranoxanthenone, Pyranothioxanthenone, and Pyranoacridone Ring Systems:  A New Class of Cytotoxic Agents

2002 ◽  
Vol 45 (12) ◽  
pp. 2599-2609 ◽  
Author(s):  
Ioannis K. Kostakis ◽  
Prokopios Magiatis ◽  
Nicole Pouli ◽  
Panagiotis Marakos ◽  
Alexios-Leandros Skaltsounis ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Cytotoxic Agents ◽  
Design Synthesis ◽  
Ring Systems ◽  
New Class ◽  
Amino Derivatives ◽  
Derivatives Of

ChemInform Abstract: Design, Synthesis, and Antiproliferative Activity of Some New Pyrazole-Fused Amino Derivatives of the Pyranoxanthenone, Pyranothioxanthenone, and Pyranoacridone Ring Systems: A New Class of Cytotoxic Agents.

ChemInform ◽  
2010 ◽  
Vol 33 (38) ◽  
pp. no-no
Author(s):  
Ioannis K. Kostakis ◽  
Prokopios Magiatis ◽  
Nicole Pouli ◽  
Panagiotis Marakos ◽  
Alexios-Leandros Skaltsounis ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Cytotoxic Agents ◽  
Design Synthesis ◽  
Ring Systems ◽  
New Class ◽  
Amino Derivatives ◽  
Derivatives Of

Design, synthesis and antiproliferative activity of the new conjugates of E7010 and resveratrol as tubulin polymerization inhibitors

2016 ◽  
Vol 14 (4) ◽  
pp. 1382-1394 ◽  
Author(s):  
Ahmed Kamal ◽  
Md. Ashraf ◽  
Shaik Thokhir Basha ◽  
S. M. Ali Hussaini ◽  
Shamshair Singh ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Tubulin Polymerization ◽  
Design Synthesis ◽  
New Class ◽  
Tubulin Polymerization Inhibitors ◽  
Amine Conjugates

A new class of (E)-N-phenyl-3-styrylpyridin-2-amine conjugates were designed and synthesized on the basis of E7010 and resveratrol scaffolds.

scholarly journals The Design, Synthesis, and Evaluation of Coumarin Ring Derivatives of the Novobiocin Scaffold that Exhibit Antiproliferative Activity

2008 ◽  
Vol 73 (22) ◽  
pp. 8901-8920 ◽  
Author(s):  
Alison C. Donnelly ◽  
Jared R. Mays ◽  
Joseph A. Burlison ◽  
John T. Nelson ◽  
George Vielhauer ◽  
...  
Keyword(s):  
Antiproliferative Activity ◽  
Design Synthesis ◽  
Derivatives Of ◽  
Coumarin Ring

Design, Synthesis and Antiproliferative Activity of Some New Azapyranoxanthenone Amino Derivatives.

ChemInform ◽  
2006 ◽  
Vol 37 (27) ◽  
Author(s):  
George Kolokythas ◽  
Nicole Pouli ◽  
Panagiotis Marakos ◽  
Harris Pratsinis ◽  
Dimitris Kletsas
Keyword(s):  
Antiproliferative Activity ◽  
Design Synthesis ◽  
Amino Derivatives

Derivatives of cis-NPCl2(NSOCl)2 and (NPCl2)2NSOCl, Part X [1] Aminolysis of cis-NPCl2(NSOF)2 and (NPCl2)2NSOF

1978 ◽  
Vol 33 (9) ◽  
pp. 964-967 ◽  
Author(s):  
H. H. Baalmann ◽  
J. C. van de Grampel
Keyword(s):  
Data Structure ◽  
Nmr Spectroscopy ◽  
Spectral Data ◽  
Room Temperature ◽  
Nucleophilic Attack ◽  
Ring Systems ◽  
Cyclic Amines ◽  
Amino Derivatives ◽  
Derivatives Of

The aminolysis of the ring systems cis-NPCl2(NSOF)2 and (NPCl2) 2NSOF by cyclic amines in acetonitrile at room temperature shows the S-F bond to be stable towards a nucleophilic attack. The amino derivatives are characterized by their spectral data. Structure assignments are based on 31P NMR spectroscopy.

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