Cdc7 Kinase Inhibitors: 5-Heteroaryl-3-Carboxamido-2-Aryl Pyrroles as Potential Antitumor Agents. 1. Lead Finding

2010 ◽  
Vol 53 (20) ◽  
pp. 7296-7315 ◽  
Author(s):  
Maria Menichincheri ◽  
Clara Albanese ◽  
Cristina Alli ◽  
Dario Ballinari ◽  
Alberto Bargiotti ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Antitumor Agents ◽  
Cdc7 Kinase ◽  
Lead Finding ◽  
Potential Antitumor

Cdc7 Kinase Inhibitors: Pyrrolopyridinones as Potential Antitumor Agents. 1. Synthesis and Structure–Activity Relationships

2008 ◽  
Vol 51 (3) ◽  
pp. 487-501 ◽  
Author(s):  
Ermes Vanotti ◽  
Raffaella Amici ◽  
Alberto Bargiotti ◽  
Jens Berthelsen ◽  
Roberta Bosotti ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Antitumor Agents ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Cdc7 Kinase ◽  
Potential Antitumor

scholarly journals First Cdc7 Kinase Inhibitors: Pyrrolopyridinones as Potent and Orally Active Antitumor Agents. 2. Lead Discovery

2009 ◽  
Vol 52 (4) ◽  
pp. 1230-1230
Author(s):  
Maria Menichincheri ◽  
Alberto Bargiotti ◽  
Jens Berthelsen ◽  
Jay A. Bertrand ◽  
Roberto Bossi ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Antitumor Agents ◽  
Lead Discovery ◽  
Cdc7 Kinase ◽  
Orally Active

Novel 1,3,5-triazine based pyrazole derivatives as potential antitumor agents and EFGR kinase inhibitors: Synthesis, cytotoxicity, DNA binding, molecular docking and DFT studies

2021 ◽  
Author(s):  
M. K. Prashanth ◽  
Raghu M.S ◽  
Pradeep Kumar C. B. ◽  
Yogesh Kumar K ◽  
Prathibha BS ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Kinase Inhibitors ◽  
Antitumor Agents ◽  
Pyrazole Derivatives ◽  
Dft Studies ◽  
Design And Synthesis ◽  
Epidermal Growth ◽  
Potential Antitumor

We herein report a design and synthesis of new 1,3,5-triazine based pyrazole derivatives (5a-i) for anticancer activity targeting epidermal growth factor (EGFR) tyrosine kinase. The newly synthesized compounds were characterized...

First Cdc7 Kinase Inhibitors: Pyrrolopyridinones as Potent and Orally Active Antitumor Agents. 2. Lead Discovery†

2009 ◽  
Vol 52 (2) ◽  
pp. 293-307 ◽  
Author(s):  
Maria Menichincheri ◽  
Alberto Bargiotti ◽  
Jens Berthelsen ◽  
Jay A. Bertrand ◽  
Roberto Bossi ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Antitumor Agents ◽  
Lead Discovery ◽  
Cdc7 Kinase ◽  
Orally Active

Design, Synthesis of Novel Quinazolone Alkaloids Derivatives as Potential Antitumor Agents

2011 ◽  
Vol 7 (4) ◽  
pp. 295-300
Author(s):  
Youguang Zheng ◽  
Min Sun ◽  
Yi Liu ◽  
Mingdong Li ◽  
Min Ji
Keyword(s):  
Antitumor Agents ◽  
Design Synthesis ◽  
Potential Antitumor

Synthesis and Biological Evaluation of Diaryl Ether Linked DC-81 Conjugates as Potential Antitumor Agents

2013 ◽  
Vol 13 (10) ◽  
pp. 1590-1600 ◽  
Author(s):  
Ahmed Kamal ◽  
A. Viswanath ◽  
M. Ramaiah ◽  
J. Murty ◽  
Farheen Sultana ◽  
...  
Keyword(s):  
Antitumor Agents ◽  
Biological Evaluation ◽  
Diaryl Ether ◽  
Synthesis And Biological Evaluation ◽  
Potential Antitumor

Synthesis and Evaluation of A New Series of Thiazole Derivatives as Potential Antitumor Agents and MMP Inhibitors

2017 ◽  
Vol 17 (5) ◽  
pp. 674-681 ◽  
Author(s):  
Zafer Asim Kaplancikli ◽  
Mehlika Dilek Altıntop ◽  
Ozlem Atli ◽  
Belgin Sever ◽  
Merve Baysal ◽  
...  
Keyword(s):  
Antitumor Agents ◽  
Thiazole Derivatives ◽  
Mmp Inhibitors ◽  
Potential Antitumor

Diaminocarbene Complexes of Palladium(II) Containing 2-Aminooxazole and 2-Aminothiazole Heterocyclic Ligands as Potential Antitumor Agents

2021 ◽  
Author(s):  
V. P. Boyarskii ◽  
A. S. Mikherdov ◽  
S. V. Baikov ◽  
P. Yu. Savko ◽  
R. V. Suezov ◽  
...  
Keyword(s):  
Antitumor Agents ◽  
Heterocyclic Ligands ◽  
Potential Antitumor

Diosgenin Derivatives as Potential Antitumor Agents: Synthesis, Cytotoxicity, and Mechanism of Action

2020 ◽  
Author(s):  
Hong Yin ◽  
Min-Jie Zhang ◽  
Ren-Feng An ◽  
Jing Zhou ◽  
Wei Liu ◽  
...  
Keyword(s):  
Mechanism Of Action ◽  
Antitumor Agents ◽  
Potential Antitumor
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