Nucleoside Transport Inhibitors: Structure−Activity Relationships for Pyrimido[5,4-d]pyrimidine Derivatives That Potentiate Pemetrexed Cytotoxicity in the Presence of α1-Acid Glycoprotein

2011 ◽  
Vol 54 (6) ◽  
pp. 1847-1859 ◽  
Author(s):  
Kappusamy Saravanan ◽  
Hannah C. Barlow ◽  
Marion Barton ◽  
A. Hilary Calvert ◽  
Bernard T. Golding ◽  
...  
Keyword(s):  
Nucleoside Transport ◽  
Pyrimidine Derivatives ◽  
Acid Glycoprotein ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Nucleoside Transport Inhibitors ◽  
Transport Inhibitors

Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency

2021 ◽  
Vol 33 ◽  
pp. 116019
Author(s):  
Ikumi Kuriwaki ◽  
Minoru Kameda ◽  
Kazuhiko Iikubo ◽  
Hiroyuki Hisamichi ◽  
Yuichiro Kawamoto ◽  
...  
Keyword(s):  
Systemic Exposure ◽  
Pyrimidine Derivatives ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Orally Active

Novel Hepatitis C virus replicon inhibitors: Synthesis and structure–activity relationships of fused pyrimidine derivatives

2012 ◽  
Vol 22 (6) ◽  
pp. 2212-2215 ◽  
Author(s):  
A. Chris Krueger ◽  
Darold L. Madigan ◽  
David W. Beno ◽  
David A. Betebenner ◽  
Robert Carrick ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Pyrimidine Derivatives ◽  
Structure Activity Relationships ◽  
Structure Activity

Organ culture as a model for investigating the effects of antimetabolites and nucleoside transport inhibitors on rodent colonic mucosa

1991 ◽  
Vol 27 (11) ◽  
pp. 873-877
Author(s):  
M. Moorghen ◽  
P. Ince ◽  
Karen J. Finney ◽  
A. J. Watson ◽  
A. L. Harris
Keyword(s):  
Organ Culture ◽  
Colonic Mucosa ◽  
Nucleoside Transport ◽  
Nucleoside Transport Inhibitors ◽  
Transport Inhibitors

Nucleoside transport inhibitors, dipyridamole and p-nitrobenzylthioinosine, selectively potentiate the antitumor activity of NB1011

2002 ◽  
Vol 13 (1) ◽  
pp. 29-36 ◽  
Author(s):  
Christopher R Boyer ◽  
Patricia L Karjian ◽  
Geoffrey M Wahl ◽  
Mark Pegram ◽  
Saskia TC Neuteboom
Keyword(s):  
Antitumor Activity ◽  
Nucleoside Transport ◽  
Nucleoside Transport Inhibitors ◽  
Transport Inhibitors

Structure−Activity Relationships of a Series of Pyrrolo[3,2-d]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists

2000 ◽  
Vol 43 (22) ◽  
pp. 4288-4312 ◽  
Author(s):  
Mark H. Norman ◽  
Ning Chen ◽  
Zhidong Chen ◽  
Christopher Fotsch ◽  
Clarence Hale ◽  
...  
Keyword(s):  
Pyrimidine Derivatives ◽  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Related Compounds

Steroid hormones are novel nucleoside transport inhibitors by competition with nucleosides for their transporters

2014 ◽  
Vol 443 (2) ◽  
pp. 505-510 ◽  
Author(s):  
Masahiro Kaneko ◽  
Fumihiko Hakuno ◽  
Hiroyasu Kamei ◽  
Daisuke Yamanaka ◽  
Kazuhiro Chida ◽  
...  
Keyword(s):  
Steroid Hormones ◽  
Nucleoside Transport ◽  
Nucleoside Transport Inhibitors ◽  
Transport Inhibitors
Sign in / Sign up

Export Citation Format

Share Document