Synthesis and Biological Evaluation of 1-Arylsulfonyl-5-(N-hydroxyacrylamide)indoles as Potent Histone Deacetylase Inhibitors with Antitumor Activity in Vivo

Biological Evaluation ◽

Novel 4-Oxoquinazoline-Based N-Hydroxypropenamides as Histone Deacetylase Inhibitors: Design, Synthesis, and Biological Evaluation

ACS Omega ◽

10.1021/acsomega.0c05870 ◽

2021 ◽

Vol 6 (7) ◽

pp. 4907-4920

Author(s):

Duong T. Anh ◽

Pham-The Hai ◽

Le D. Huy ◽

Hoang B. Ngoc ◽

Trinh T. M. Ngoc ◽

...

Keyword(s):

Histone Deacetylase ◽

Biological Evaluation ◽

Design Synthesis ◽

Evaluation of the In vitro and In vivo Antitumor Activity of Histone Deacetylase Inhibitors for the Therapy of Retinoblastoma

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-4836 ◽

2008 ◽

Vol 14 (10) ◽

pp. 3113-3123 ◽

Cited By ~ 47

Author(s):

Clifton Lee Dalgard ◽

Kurtis R. Van Quill ◽

Joan M. O'Brien

Keyword(s):

Antitumor Activity ◽

Histone Deacetylase ◽

In Vivo Antitumor Activity

Synthesis and biological evaluation of acridine-based histone deacetylase inhibitors as multitarget agents against Alzheimer’s disease

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112193 ◽

2020 ◽

Vol 192 ◽

pp. 112193 ◽

Cited By ~ 3

Author(s):

Hui-Ju Tseng ◽

Mei-Hsiang Lin ◽

Young-Ji Shiao ◽

Ying-Chen Yang ◽

Jung-Chun Chu ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Histone Deacetylase ◽

Biological Evaluation ◽

Design, synthesis, and biological evaluation of novel 2,4-thiazolidinedione derivatives as histone deacetylase inhibitors targeting liver cancer cell line

Medicinal Chemistry Research ◽

10.1007/s00044-011-9623-3 ◽

2011 ◽

Vol 21 (7) ◽

pp. 1156-1165 ◽

Cited By ~ 17

Author(s):

Rhea Mohan ◽

Ajit K. Sharma ◽

Sanjay Gupta ◽

C. S. Ramaa

Keyword(s):

Liver Cancer ◽

Cell Line ◽

Histone Deacetylase ◽

Cancer Cell ◽

Cancer Cell Line ◽

Biological Evaluation ◽

Liver Cancer Cell ◽

Design Synthesis ◽

Design, synthesis and biological evaluation of 4-piperidin-4-yl-triazole derivatives as novel histone deacetylase inhibitors

BioScience Trends ◽

10.5582/bst.2019.01055 ◽

2019 ◽

Vol 13 (2) ◽

pp. 197-203 ◽

Cited By ~ 2

Author(s):

He Miao ◽

Jianjun Gao ◽

Zishuo Mou ◽

Baolei Wang ◽

Li Zhang ◽

...

Keyword(s):

Histone Deacetylase ◽

Biological Evaluation ◽

Design Synthesis ◽

Triazole Derivatives ◽

Design, synthesis and biological evaluation of coumarin-based N-hydroxycinnamamide derivatives as novel histone deacetylase inhibitors with anticancer activities

Bioorganic Chemistry ◽

10.1016/j.bioorg.2020.104023 ◽

2020 ◽

Vol 101 ◽

pp. 104023 ◽

Cited By ~ 1

Author(s):

Jiaoli Ding ◽

Jing Liu ◽

Zhipeng Zhang ◽

Jie Guo ◽

Maojun Cheng ◽

...

Keyword(s):

Histone Deacetylase ◽

Biological Evaluation ◽

Anticancer Activities ◽

Design Synthesis ◽

A Novel Series of Potent and Selective Ketone Histone Deacetylase Inhibitors with Antitumor Activity in Vivo

Journal of Medicinal Chemistry ◽

10.1021/jm800079s ◽

2008 ◽

Vol 51 (8) ◽

pp. 2350-2353 ◽

Cited By ~ 38

Author(s):

Philip Jones ◽

Sergio Altamura ◽

Raffaele De Francesco ◽

Odalys Gonzalez Paz ◽

Olaf Kinzel ◽

...

Keyword(s):

Antitumor Activity ◽

Histone Deacetylase ◽

Histone Deacetylase Inhibitors

Design, synthesis and biological evaluation of novel 2-aminobenzamides containing dithiocarbamate moiety as histone deacetylase inhibitors and potent antitumor agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.08.041 ◽

2018 ◽

Vol 143 ◽

pp. 320-333 ◽

Cited By ~ 14

Author(s):

Rui Xie ◽

Yan Li ◽

Pingwah Tang ◽

Qipeng Yuan

Keyword(s):

Histone Deacetylase ◽

Antitumor Agents ◽

Biological Evaluation ◽

Design Synthesis ◽

Design, synthesis and biological evaluation of novel histone deacetylase inhibitors based on virtual screening

Acta Pharmaceutica Sinica B ◽

10.1016/j.apsb.2011.10.002 ◽

2011 ◽

Vol 1 (4) ◽

pp. 240-247 ◽

Cited By ~ 9

Author(s):

Hui Lu ◽

Ya-dong Chen ◽

Bo Yang ◽

Qi-dong You

Keyword(s):

Virtual Screening ◽

Histone Deacetylase ◽

Biological Evaluation ◽

Design Synthesis ◽

Design, synthesis and biological evaluation of indeno[1,2-d]thiazole derivatives as potent histone deacetylase inhibitors

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2013.04.004 ◽

2013 ◽

Vol 23 (11) ◽

pp. 3200-3203 ◽

Cited By ~ 12

Author(s):

Ming Zhou ◽

Chengqing Ning ◽

Ruihuan Liu ◽

Yujun He ◽

Niefang Yu

Keyword(s):

Histone Deacetylase ◽

Biological Evaluation ◽

Thiazole Derivatives ◽

Design Synthesis ◽