Design, Synthesis, and Biological Evaluation of Novel Constrainedmeta-Substituted Phenyl Propanoic Acids as Peroxisome Proliferator-Activated Receptor α and γ Dual Agonists

Design Synthesis ◽

Design, synthesis and biological evaluation of a class of bioisosteric oximes of the novel dual peroxisome proliferator-activated receptor α/γ ligand LT175

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.11.044 ◽

2015 ◽

Vol 90 ◽

pp. 583-594 ◽

Cited By ~ 16

Author(s):

Luca Piemontese ◽

Giuseppe Fracchiolla ◽

Antonio Carrieri ◽

Mariagiovanna Parente ◽

Antonio Laghezza ◽

...

Keyword(s):

Biological Evaluation ◽

Peroxisome Proliferator ◽

The Novel ◽

Design Synthesis ◽

Design, synthesis, and biological evaluation of a series of alkoxy-3-indolylacetic acids as peroxisome proliferator-activated receptor γ/δ agonists

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2015.04.046 ◽

2015 ◽

Vol 23 (13) ◽

pp. 3322-3336 ◽

Cited By ~ 7

Author(s):

Hyo Jin Gim ◽

Hua Li ◽

Ji Hye Jeong ◽

Su Jeong Lee ◽

Mi-Kyung Sung ◽

...

Keyword(s):

Biological Evaluation ◽

Peroxisome Proliferator ◽

Design Synthesis ◽

Design, synthesis, and biological evaluation of a novel dual peroxisome proliferator-activated receptor alpha/delta agonist for the treatment of diabetic kidney disease through anti-inflammatory mechanisms

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113388 ◽

2021 ◽

Vol 218 ◽

pp. 113388

Author(s):

Kai Liu ◽

Xing Zhao ◽

Xue Qi ◽

Dong-Liang Hou ◽

Hao-Bin Li ◽

...

Keyword(s):

Kidney Disease ◽

Diabetic Kidney Disease ◽

Biological Evaluation ◽

Peroxisome Proliferator ◽

Design Synthesis ◽

Diabetic Kidney ◽

Receptor Alpha ◽

Anti Inflammatory ◽

Peroxisome proliferator-activated receptor-γ mediates the anti-inflammatory effect of 3-hydroxy-4-pyridinecarboxylic acid derivatives: Synthesis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2013.01.024 ◽

2013 ◽

Vol 62 ◽

pp. 486-497 ◽

Cited By ~ 21

Author(s):

Paola Brun ◽

Annalisa Dean ◽

Valerio Di Marco ◽

Pathak Surajit ◽

Ignazio Castagliuolo ◽

...

Keyword(s):

Biological Evaluation ◽

Peroxisome Proliferator ◽

Pyridinecarboxylic Acid ◽

Anti Inflammatory ◽

Synthesis And Biological Evaluation ◽

Inflammatory Effect

Synthesis and Biological Evaluation of 2-Heteroarylthioalkanoic Acid Analogues of Clofibric Acid as Peroxisome Proliferator-Activated Receptor α Agonists

Journal of Medicinal Chemistry ◽

10.1021/jm900878u ◽

2009 ◽

Vol 52 (20) ◽

pp. 6224-6232 ◽

Cited By ~ 15

Author(s):

Letizia Giampietro ◽

Alessandra Ammazzalorso ◽

Antonella Giancristofaro ◽

Fabio Lannutti ◽

Giancarlo Bettoni ◽

...

Keyword(s):

Biological Evaluation ◽

Clofibric Acid ◽

Peroxisome Proliferator ◽

Novel Oxazolidinone-Based Peroxisome Proliferator Activated Receptor Agonists: Molecular Modeling, Synthesis, and Biological Evaluation

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.5b00849 ◽

2015 ◽

Vol 58 (16) ◽

pp. 6639-6652 ◽

Cited By ~ 6

Author(s):

N. Fresno ◽

M. Macías-González ◽

A. Torres-Zaguirre ◽

M. Romero-Cuevas ◽

P. Sanz-Camacho ◽

...

Keyword(s):

Molecular Modeling ◽

Biological Evaluation ◽

Peroxisome Proliferator ◽

Receptor Agonists ◽

Design, Synthesis and Biological Evaluation of some Chalcone Derivatives as Potential Pancreatic Lipase Inhibitors

10.3390/ecsoc-17-b024 ◽

2013 ◽

Author(s):

Dao Tran

Keyword(s):

Pancreatic Lipase ◽

Biological Evaluation ◽

Design Synthesis ◽

Chalcone Derivatives ◽

Pancreatic Lipase Inhibitors ◽

Faculty Opinions recommendation of Structure-Based Design, Synthesis, and Biological Evaluation of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726271231.793520213 ◽

2016 ◽

Author(s):

Miles Congreve ◽

Mark Pickworth

Keyword(s):

G Protein ◽

Biological Evaluation ◽

Receptor Kinase ◽

G Protein Coupled Receptor ◽

Design Synthesis ◽

G Protein Coupled ◽

Design, Synthesis and Biological Evaluation of Hybrid Molecules Containing Conjugated Styryl Ketone and α-Bromoacryloyl Moieties

Letters in Drug Design & Discovery ◽

10.2174/157018012799079842 ◽

2012 ◽

Vol 9 (2) ◽

pp. 140-152 ◽

Cited By ~ 1

Author(s):

Romeo Romagnoli ◽

Pier Giovanni Baraldi ◽

Olga Cruz-Lopez ◽

Maria Kimatrai Salvador ◽

Delia Preti ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Hybrid Molecules ◽

Design, Synthesis and Biological Evaluation of Novel Aminosaccharide Derivatives of Combretastatin A-4

Letters in Drug Design & Discovery ◽

10.2174/15701808113109990024 ◽

2013 ◽

Vol 10 (10) ◽

pp. 935-941

Author(s):

Yan Tang ◽

Zhewei Tu ◽

Jing Sun ◽

Xiong Zhu ◽

Kun Liu ◽

...

Keyword(s):

Biological Evaluation ◽

Design Synthesis ◽

Synthesis And Biological Evaluation ◽

Derivatives Of