Discovery of 1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9H-purin-6-yl]-4-ethylaminopiperidine-4-carboxylic Acid Amide Hydrochloride (CP-945,598), a Novel, Potent, and Selective Cannabinoid Type 1 Receptor Antagonist

2009 ◽  
Vol 52 (2) ◽  
pp. 234-237 ◽  
Author(s):  
David A. Griffith ◽  
John R. Hadcock ◽  
Shawn C. Black ◽  
Philip A. Iredale ◽  
Philip A. Carpino ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Receptor Antagonist ◽  
Acid Amide ◽  
Carboxylic Acid Amide ◽  
Cannabinoid Type 1 Receptor

Rhodium catalyzed one-step hydroamidation of cyclopentadiene and dicyclopentadiene

2015 ◽  
Vol 5 (5) ◽  
pp. 2783-2787 ◽  
Author(s):  
Arno Behr ◽  
Denys Levikov ◽  
Edward Nürenberg
Keyword(s):  
Carboxylic Acid ◽  
Acid Amide ◽  
Amide Group ◽  
Carboxylic Acid Amide ◽  
Direct Route ◽  
One Step ◽  
Pharmaceutical Industries

The carboxylic acid amide group is of great importance in the contemporary chemical and pharmaceutical industries. A one-step rhodium catalyzed direct route from alkene to amide is presented via the hydroamidation reaction of cyclopentadiene and dicyclopentadiene.

Solvent- and catalyst-free, quantitative protection of hydroxyl, thiol, carboxylic acid, amide and heterocyclic amino functional groups

2016 ◽  
Vol 18 (23) ◽  
pp. 6209-6214 ◽  
Author(s):  
Mia L. Jawor ◽  
Basil M. Ahmed ◽  
Gellert Mezei
Keyword(s):  
Carboxylic Acid ◽  
Functional Groups ◽  
Acid Amide ◽  
Waste Materials ◽  
Carboxylic Acid Amide ◽  
Catalyst Free

Various substrates are quantitatively protected by 3,4-dihydro-2H-pyran at 125 °C in the absence of any additional chemicals, without generating any waste materials.

Tetra-primer ARMS PCR for rapid detection and characterisation ofPlasmopara viticolaphenotypes resistant to carboxylic acid amide fungicides

2017 ◽  
Vol 73 (8) ◽  
pp. 1655-1660 ◽  
Author(s):  
Hao Zhang ◽  
Fanfang Kong ◽  
Xina Wang ◽  
Lisha Liang ◽  
Cor D Schoen ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Rapid Detection ◽  
Acid Amide ◽  
Carboxylic Acid Amide ◽  
Arms Pcr

Synthesis and separation of substituted cyclopropane carboxylic acid amide isomers

2001 ◽  
Vol 12 (9) ◽  
pp. 1287-1292 ◽  
Author(s):  
Zoltán Finta ◽  
Zoltán Hell ◽  
József Bálint ◽  
Adrienn Takács ◽  
László Párkányi ◽  
...  
Keyword(s):  
Carboxylic Acid ◽  
Acid Amide ◽  
Carboxylic Acid Amide

scholarly journals Possible Therapeutic Doses of Cannabinoid Type 1 Receptor Antagonist Reverses Key Alterations in Fragile X Syndrome Mouse Model

Genes ◽  
2016 ◽  
Vol 7 (9) ◽  
pp. 56 ◽  
Author(s):  
Maria Gomis-González ◽  
Arnau Busquets-Garcia ◽  
Carlos Matute ◽  
Rafael Maldonado ◽  
Susana Mato ◽  
...  
Keyword(s):  
Mouse Model ◽  
Receptor Antagonist ◽  
Fragile X Syndrome ◽  
Fragile X ◽  
Cannabinoid Type 1 Receptor ◽  
Therapeutic Doses
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