Synthesis and Stereochemical Structure−Activity Relationships of 1,3-Dioxoperhydropyrido[1,2-c]pyrimidine Derivatives:  Potent and Selective Cholecystokinin-A Receptor Antagonists

1997 ◽  
Vol 40 (21) ◽  
pp. 3402-3407 ◽  
Author(s):  
Mercedes Martín-Martínez ◽  
José M. Bartolomé-Nebreda ◽  
Isabel Gómez-Monterrey ◽  
Rosario González-Muñiz ◽  
M. Teresa García-López ◽  
...  
Keyword(s):  
Pyrimidine Derivatives ◽  
Receptor Antagonists ◽  
Stereochemical Structure ◽  
Structure Activity Relationships ◽  
Structure Activity

Structure−Activity Relationships of a Series of Pyrrolo[3,2-d]pyrimidine Derivatives and Related Compounds as Neuropeptide Y5 Receptor Antagonists

2000 ◽  
Vol 43 (22) ◽  
pp. 4288-4312 ◽  
Author(s):  
Mark H. Norman ◽  
Ning Chen ◽  
Zhidong Chen ◽  
Christopher Fotsch ◽  
Clarence Hale ◽  
...  
Keyword(s):  
Pyrimidine Derivatives ◽  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Related Compounds

Synthesis, Molecular Pharmacology, and Structure–Activity Relationships of 3-(Indanoyl)indoles as Selective Cannabinoid Type 2 Receptor Antagonists

2021 ◽  
Author(s):  
Harvey F. Fulo ◽  
Amal Shoeib ◽  
Christian V. Cabanlong ◽  
Alexander H. Williams ◽  
Chang-Guo Zhan ◽  
...  
Keyword(s):  
Molecular Pharmacology ◽  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Structure Activity

Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency

2021 ◽  
Vol 33 ◽  
pp. 116019
Author(s):  
Ikumi Kuriwaki ◽  
Minoru Kameda ◽  
Kazuhiko Iikubo ◽  
Hiroyuki Hisamichi ◽  
Yuichiro Kawamoto ◽  
...  
Keyword(s):  
Systemic Exposure ◽  
Pyrimidine Derivatives ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Orally Active

Novel Hepatitis C virus replicon inhibitors: Synthesis and structure–activity relationships of fused pyrimidine derivatives

2012 ◽  
Vol 22 (6) ◽  
pp. 2212-2215 ◽  
Author(s):  
A. Chris Krueger ◽  
Darold L. Madigan ◽  
David W. Beno ◽  
David A. Betebenner ◽  
Robert Carrick ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Pyrimidine Derivatives ◽  
Structure Activity Relationships ◽  
Structure Activity

Selective endothelin A receptor antagonists. 2. Discovery and structure-activity relationships of 5-ketopentanoic acid derivatives

1997 ◽  
Vol 32 (6) ◽  
pp. 515-522 ◽  
Author(s):  
P.C. Astles ◽  
T.J. Brown ◽  
N.V. Harris ◽  
M.F. Harper ◽  
C McCarthy ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Endothelin A Receptor ◽  
Endothelin A

Synthesis and structure–activity relationships of ( R )-1-alkyl-3-[2-(2-amino)phenethyl]-5-(2-fluorophenyl)-6-methyluracils as human GnRH receptor antagonists

2004 ◽  
Vol 14 (9) ◽  
pp. 2269-2274 ◽  
Author(s):  
Martin W Rowbottom ◽  
Fabio C Tucci ◽  
Yun-Fei Zhu ◽  
Zhiqiang Guo ◽  
Timothy D Gross ◽  
...  
Keyword(s):  
Gnrh Receptor ◽  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Structure Activity

Structure–activity relationships of a novel series of melanin-concentrating hormone (MCH) receptor antagonists

2004 ◽  
Vol 14 (15) ◽  
pp. 4099-4102 ◽  
Author(s):  
Rosa Arienzo ◽  
David E Clark ◽  
Sue Cramp ◽  
Stephen Daly ◽  
Hazel J Dyke ◽  
...  
Keyword(s):  
Receptor Antagonists ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Melanin Concentrating Hormone

ChemInform Abstract: Indole Amide Derivatives: Synthesis, Structure-Activity Relationships, and Molecular Modeling Studies of a New Series of Histamine H1-Receptor Antagonists.

ChemInform ◽  
2010 ◽  
Vol 30 (29) ◽  
pp. no-no
Author(s):  
Sandra Battaglia ◽  
Enrico Boldrini ◽  
Federico Da Settimo ◽  
Giulio Dondio ◽  
Concettina La Motta ◽  
...  
Keyword(s):  
Molecular Modeling ◽  
H1 Receptor ◽  
Receptor Antagonists ◽  
Histamine H1 Receptor ◽  
Structure Activity Relationships ◽  
Structure Activity ◽  
Modeling Studies ◽  
Amide Derivatives ◽  
Molecular Modeling Studies
Sign in / Sign up

Export Citation Format

Share Document