scholarly journals Asymmetric Synthesis of New Chiral Europium N,N'-Disuccinate Complexes: Shift Reagents for Aqueous Solutions and Application in the Enantiomeric Excess Determination of Amino Acids

1994 ◽  
Vol 59 (24) ◽  
pp. 7453-7458 ◽  
Author(s):  
Ron Hulst ◽  
N. Koen de Vries ◽  
Ben L. Feringa
Keyword(s):  
Amino Acids ◽  
Aqueous Solutions ◽  
Asymmetric Synthesis ◽  
Enantiomeric Excess ◽  
Shift Reagents

Simultaneous determination of the concentration and enantiomeric excess of amino acids with a coumarin-derived achiral probe

2021 ◽  
Vol 13 (16) ◽  
pp. 1905-1910
Author(s):  
Lamei Yang ◽  
Feng Luo ◽  
Weili Wei
Keyword(s):  
Amino Acids ◽  
Simultaneous Determination ◽  
Enantiomeric Excess ◽  
Chiral Analysis

An achiral easy-to-synthesize coumarin aldehyde probe was designed and synthesized for chiral analysis of amino acids.

31P NMR Spectroscopy as a Powerful Tool for the Determination of Enantiomeric Excess and Absolute Configurations of α-Amino Acids

2003 ◽  
Vol 42 (4) ◽  
pp. 1006-1013 ◽  
Author(s):  
Judith Bravo ◽  
Carlos Cativiela ◽  
Julio E. Chaves ◽  
Rafael Navarro ◽  
Esteban P. Urriolabeitia
Keyword(s):  
Amino Acids ◽  
Nmr Spectroscopy ◽  
31P Nmr ◽  
Enantiomeric Excess ◽  
31P Nmr Spectroscopy

scholarly journals Taking advantage of Co(ii) induced enhanced VCD for the fast and sensitive determination of enantiomeric excess

2017 ◽  
Vol 15 (46) ◽  
pp. 9800-9803 ◽  
Author(s):  
Lorenzo Arrico ◽  
Gaetano Angelici ◽  
Lorenzo Di Bari
Keyword(s):  
Amino Acids ◽  
Enantiomeric Excess ◽  
Sensitive Determination

Large Co(ii)-induced VCD signals provide a method for determining the enantiomeric excess of α-amino acids. This strategy can be followed for building new VCD protocols.

Asymmetric Synthesis of Enantiomerically Enriched a-Amino Acids Containing 2-Furyl- and 2-Thienyl-1,2,4-triazoles in the Side-Chain

2014 ◽  
Vol 69 (4) ◽  
pp. 451-460 ◽  
Author(s):  
Ashot S. Saghyan ◽  
Hayarpi M. Simonyan ◽  
Satenik G. Petrosyan ◽  
Anna F. Mkrtchyan ◽  
Lilit V. Khachatryan ◽  
...  
Keyword(s):  
Amino Acids ◽  
Schiff Base ◽  
Asymmetric Synthesis ◽  
Efficient Method ◽  
Enantiomeric Excess ◽  
Side Chain ◽  
Chiral Auxiliaries ◽  
Enantiomerically Pure ◽  
Dehydroamino Acids ◽  
Hydrolysis Of

An efficient method for the asymmetric synthesis of a-amino acids, containing furyl- and thiophenyl-substituted triazoles in their side-chain, is reported. The strategy relies on Michael addition of 3,4,5-substituted 1,2,4-triazoles to the C=C bond of chiral NiII complexes containing the Schiff base formed from dehydroamino acids (dehydroalanine and (E + Z)-dehydroaminobutyric acid) and from chiral auxiliaries, i. e. (S)-2-N-(N0-benzylprolyl)aminobenzophenone and (S)-2-N- (N0-2-chlorobenzylprolyl) aminobenzophenone. The reactions proceeded with good to very good diastereoselectivity. Hydrolysis of the diastereomeric mixtures of metal complexes afforded the enantiomerically pure a-amino acids with high enantiomeric excess (ee> 98%).

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