1,3-Dipolar Cycloaddition Reactions of Nitrile Oxides with 1,3-Dioxolanes of .alpha.,.beta.-Unsaturated Aldehydes

1995 ◽  
Vol 60 (23) ◽  
pp. 7701-7705 ◽  
Author(s):  
Ta-Jung Lu ◽  
Jyh-Ferng Yang ◽  
Lij-Jyi Sheu
Keyword(s):  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Nitrile Oxides ◽  
Unsaturated Aldehydes ◽  
Alpha Beta

ChemInform Abstract: 1,3-Dipolar Cycloaddition Reactions of Nitrile Oxides with 1,3- Dioxolanes of α,β-Unsaturated Aldehydes.

ChemInform ◽  
2010 ◽  
Vol 27 (14) ◽  
pp. no-no
Author(s):  
T.-J. LU ◽  
J.-F. YANG ◽  
L.-J. SHEU
Keyword(s):  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Nitrile Oxides ◽  
Unsaturated Aldehydes

ChemInform Abstract: 1,3-DIPOLAR CYCLOADDITION REACTIONS OF 2-PHENYL-4-ARYLIDENE-5(4H)-OXAZOLONES WITH NITRILE OXIDES

1985 ◽  
Vol 16 (21) ◽  
Author(s):  
N. G. ARGYROPOULOS ◽  
E. COUTOULI-ARGYROPOULOU
Keyword(s):  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Nitrile Oxides

1,3-Dipolar cycloaddition reactions of nitrile oxides in the synthesis of natural compounds and their analogues

2001 ◽  
Vol 70 (8) ◽  
pp. 641-653 ◽  
Author(s):  
Anna I Kotyatkina ◽  
Vladimir N Zhabinsky ◽  
Vladimir A Khripach
Keyword(s):  
Natural Compounds ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Nitrile Oxides

Efficient one pot and chemoselective synthesis of functionalized 3-bromo-4,5-dihydroisoxazole derivatives via 1,3-dipolar cycloaddition reactions of nitrile oxides

Tetrahedron ◽  
2017 ◽  
Vol 73 (48) ◽  
pp. 6706-6711 ◽  
Author(s):  
Abdolali Alizadeh ◽  
Atefeh Roosta ◽  
Reza Rezaiyehrad ◽  
Mohammadreza Halvagar
Keyword(s):  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
One Pot ◽  
Nitrile Oxides ◽  
Chemoselective Synthesis

Spiroheterocycles via Regioselective Cycloaddition Reactions of Nitrile Oxides with 5-Methylene-1H-pyrrol-2(5H)-ones

2010 ◽  
Vol 63 (3) ◽  
pp. 445 ◽  
Author(s):  
Nicola J. Beattie ◽  
Craig L. Francis ◽  
Andris J. Liepa ◽  
G. Paul Savage
Keyword(s):  
Cycloaddition Reaction ◽  
Biphasic System ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Nitrile Oxides ◽  
Facial Selectivity

Substituted 5-methylene-1H-pyrrol-2(5H)-ones underwent a 1,3-dipolar cycloaddition reaction with nitrile oxides to give the corresponding spiro heterocycles. Critical to this reaction was the development of a biphasic system for base-induced dehydrohalogenation of hydroximoyl chlorides, to give nitrile oxides, in the presence of a base-sensitive dipolarophile. A substituted N-tolyl 5-methylene-1H-pyrrol-2(5H)-one exhibited atropisomerism, which in turn led to a 4:1 facial selectivity during cycloaddition.

1,3-Dipolar Cycloadditions of a Chiral Oxazolidinone With Nitrones and Nitrile Oxides

1995 ◽  
Vol 48 (9) ◽  
pp. 1511 ◽  
Author(s):  
SG Pyne ◽  
J Safaei-G ◽  
BW Skelton ◽  
AH White
Keyword(s):  
Single Crystal ◽  
Hydrogen Atmosphere ◽  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
The Novel ◽  
X Ray ◽  
Dipolar Cycloadditions ◽  
Nitrile Oxides ◽  
Exocyclic Methylene

The 1,3-dipolar cycloaddition reactions of the chiral oxazolidinone (1) and nitrones are highly regioselective and only 5,5-disubstituted isoxazolidine adducts are formed. These reactions occur under equilibrating conditions to give the more stable adducts that result from addition to the exocyclic methylene of (1) from the sterically more hindered π-face. The endo adducts are generally thermodynamically favoured. In one case the novel azetidine (21) was formed from the treatment of the adduct (4a) with palladium hydroxide on carbon under a hydrogen atmosphere. The major adducts from the reaction of (1) and nitrile oxides (16a,b) had the expected stereochemistry, addition of the 1,3-dipole having occurred from the less hindered π-face of the exocyclic methylene of (1). The stereochemistry of many of these products has been elucidated by single-crystal X-ray structural determinations.

1,3-dipolar cycloaddition reactions of nitrile oxides to prop-1-ene-1,3-sultone

2003 ◽  
Vol 40 (6) ◽  
pp. 1071-1074 ◽  
Author(s):  
Li Tian ◽  
Guo-Yan Xu ◽  
Yong Ye ◽  
Lun-Zu Liu
Keyword(s):  
Dipolar Cycloaddition ◽  
Cycloaddition Reactions ◽  
Nitrile Oxides
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