A New Titanium Tetrachloride Mediated Annulation of α-Aryl-Substituted Carbonyl Compounds with Alkynes:  A Simple and Highly Efficient Method for the Regioselective Synthesis of Polysubstituted Naphthalene Derivatives

2003 ◽  
Vol 68 (20) ◽  
pp. 7915-7917 ◽  
Author(s):  
George W. Kabalka ◽  
Yuhong Ju ◽  
Zhongzhi Wu

Synlett ◽  
2019 ◽  
Vol 30 (15) ◽  
pp. 1810-1814 ◽  
Author(s):  
Enoch A. Mensah ◽  
Shawn D. Green ◽  
Jesse West ◽  
Tyler Kindoll ◽  
Brenda Lazaro-Martinez

The development of a new, highly efficient, and simple method for masking carbonyl groups as acetals and ketals is described. This methodology relies on the nature of the palladium catalyst to direct the acetalization/ketalization reaction. This new protocol is mild and proceed with a very low catalyst loading at ambient temperatures. The method has been extended to a wide variety of different carbonyl compounds with various steric encumbrances to form the corresponding acetals and ketals in excellent yields.



Synthesis ◽  
2005 ◽  
Vol 2005 (02) ◽  
pp. 183-186 ◽  
Author(s):  
Takeshi Oriyama ◽  
Katsuyuki Iwanami ◽  
Hana Seo ◽  
Yuki Tobita








2004 ◽  
Vol 45 (41) ◽  
pp. 7719-7721 ◽  
Author(s):  
Jian-Ying Qi ◽  
Jian-Xin Ji ◽  
Chi-Hung Yueng ◽  
Hoi-Lun Kwong ◽  
Albert S.C. Chan






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