In many multiphase fluidic processes, such as in petroleum extraction and biochemical analysis involving microscale conduits, the lodging of immiscible droplets often leads to disastrous flow blockage. Without a thin-film lubrication layer surrounding the adhered droplets, a significantly higher threshold pressure gradient is required to reinitiate bulk flows. In this work, we investigate the surface tension-driven thin-film drainage process that leads to droplet adhesion and study how electrostatic repulsion between a charged droplet interface and a charged conduit wall can prevent direct contact between the two. We report on our multiphysics computational results of an oversized gas droplet in a water-filled flow microchannel under the influence of surface tension and interfacial electrostatic forces.