Helix-Coil Stability for the Naturally Occurring Amino Acids in Water. VIII. Valine Parameters from Random Poly(hydroxypropylglutamine-co-L-valine) and Poly(hydroxybutylglutamine-co-L-valine)

Little evidence is available for the physiological function of D-amino acids in species other than bacteria. Here we demonstrate that naturally occurring freed -aspartate (D-Asp) is present in all magnocellular neurons of rat hypothalamus. The levels of this naturally occurring D-amino acid were elevated during lactation and returned to normal thereafter in the magnocellular neurosecretory system, which produces oxytocin, a hormone responsible for milk ejection during lactation. Intraperitoneal injections of D-Asp reproducibly increased oxytocin gene expression and decreased the concentration of circulating oxytocin in vivo. Similar changes were observed in the vasopressin system. These results provide evidence for the role(s) of naturally occurring free D-Asp in mammalian physiology. The findings argue against the conventional concept that only L-stereoisomers of amino acids are functional in higher species.

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Naturally Occurring Food Toxicants: Toxic Amino Acids

Handbook of Naturally Occurring Food Toxicants ◽

10.1201/9781351072946-1 ◽

2018 ◽

pp. 3-14

Author(s):

Christine S. Evans

Keyword(s):

Amino Acids ◽

Naturally Occurring ◽

Food Toxicants

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Adsorption of carbon dioxide on naturally occurring solid amino acids

Journal of Environmental Chemical Engineering ◽

10.1016/j.jece.2016.06.007 ◽

2016 ◽

Vol 4 (3) ◽

pp. 3170-3176 ◽

Cited By ~ 8

Author(s):

Sreedipta Chatterjee ◽

Sadhana Rayalu ◽

Spas D. Kolev ◽

Reddithota J. Krupadam

Keyword(s):

Carbon Dioxide ◽

Amino Acids ◽

Naturally Occurring

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Transporters in Arabidopsis roots mediating uptake of amino acids at naturally occurring concentrations

New Phytologist ◽

10.1111/j.1469-8137.2011.03699.x ◽

2011 ◽

Vol 191 (2) ◽

pp. 459-467 ◽

Cited By ~ 62

Author(s):

Henrik Svennerstam ◽

Sandra Jämtgård ◽

Iftikhar Ahmad ◽

Kerstin Huss-Danell ◽

Torgny Näsholm ◽

...

Keyword(s):

Amino Acids ◽

Naturally Occurring

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DATA ON THE NATURALLY OCCURRING AMINO ACIDS

Handbook of Biochemistry and Molecular Biology ◽

10.1201/b10501-2 ◽

2010 ◽

pp. 7-42

Author(s):

Elizabeth Dodd Mooz

Keyword(s):

Amino Acids ◽

Naturally Occurring

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Effects of some Amino-acid and Purine Antagonists on Chick Embryos

Development ◽

10.1242/dev.6.2.365 ◽

1958 ◽

Vol 6 (2) ◽

pp. 365-372

Author(s):

C. H. Waddington ◽

Margaret Perry

Keyword(s):

Amino Acids ◽

Amino Acid ◽

Effective Concentration ◽

Metabolic Inhibitors ◽

Chick Embryos ◽

Purine Analogue ◽

Know How ◽

Naturally Occurring ◽

Different Types ◽

Strong Action

Several authors have studied the effects on developing embryos of substances which are analogues of naturally occurring amino-acids and purines, and known to act, in other systems, as metabolic inhibitors. It was emphasized by Waddington, Feldman, & Perry (1955) that any particular substance may exhibit very different effects in embryos of different types. They found, for instance, that the purine analogue 8-azaguanine has a very strong action in the chick and a much lesser one in the newt embryo. It is therefore necessary to consider the various classes of embryos separately. In this communication we shall be concerned only with chick embryos. Substances under test can be administered to such embryos by injection through the shell, as was done in the paper cited above With this technique it is impossible to know how much diffusion takes place of the substance injected, and one cannot therefore be certain of the effective concentration which actually reaches the embryo.

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