A Novel Anabolic Agent: A Simvastatin Analogue without HMG-CoA Reductase Inhibitory Activity

2014 ◽  
Vol 16 (17) ◽  
pp. 4376-4379 ◽  
Author(s):  
Kuang-Chan Hsieh ◽  
Chai-Lin Kao ◽  
Chien-Wei Feng ◽  
Zhi-Hong Wen ◽  
Hsin-Fang Chang ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Hmg Coa Reductase ◽  
Anabolic Agent ◽  
Coa Reductase

In vitro antioxidant, antiglycation, and enzymatic inhibitory activity against α-glucosidase, α-amylase, lipase and HMG-CoA reductase of Terminalia boivinii Tul.

2021 ◽  
pp. 102235
Author(s):  
Bongani Sicelo Dlamini ◽  
Carlos Eduardo Hernandez ◽  
Chiy-Rong Chen ◽  
Wen-Ling Shih ◽  
Jue-Liang Hsu ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Hmg Coa Reductase ◽  
Coa Reductase

scholarly journals HMG-CoA reductase inhibitory activity and phytocomponent investigation of Basella alba leaf extract as a treatment for hypercholesterolemia

2015 ◽  
pp. 509 ◽  
Author(s):  
Gunasekaran Baskaran ◽  
Mohd Yunus Shukor ◽  
Shamala Salvamani ◽  
Siti Aqlima Ahmad ◽  
Noor Azmi Shaharuddin ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Leaf Extract ◽  
Hmg Coa Reductase ◽  
Basella Alba ◽  
Coa Reductase

scholarly journals Influence of extraction methods of bay leaves (Syzygium polyanthum) on antioxidant and HMG-CoA Reductase inhibitory activity

Heliyon ◽  
2019 ◽  
Vol 5 (4) ◽  
pp. e01485
Author(s):  
Lanny Hartanti ◽  
Stefania Maureen Kasih Yonas ◽  
Josianne Jacqlyn Mustamu ◽  
Sumi Wijaya ◽  
Henry Kurnia Setiawan ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Extraction Methods ◽  
Hmg Coa Reductase ◽  
Coa Reductase

scholarly journals HMG-CoA Reductase Inhibitory Activity of Garcinia latissima Miq. Mesocarp Water Extract for Herbal Tea

2018 ◽  
Vol 10 (6s) ◽  
pp. s141-s146
Author(s):  
Herra Williany Monalissa ◽  
Berna Elya ◽  
Nuraini Puspitasari
Keyword(s):  
Inhibitory Activity ◽  
Water Extract ◽  
Herbal Tea ◽  
Hmg Coa Reductase ◽  
Coa Reductase

In silico Screening of Selected Flavanones for HMG CoA Reductase Inhibitory Activity

2020 ◽  
Vol 14 (5) ◽  
pp. 128-139
Author(s):  
Tan Ker Ying ◽  
Mohamed Saleem Abdul Shukkoor ◽  
Shaik Ibrahim Khalivulla
Keyword(s):  
Inhibitory Activity ◽  
In Silico ◽  
In Silico Screening ◽  
Hmg Coa Reductase ◽  
Coa Reductase

Development of liposomal formulations to potentiate natural lovastatin inhibitory activity towards 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase

2018 ◽  
Vol 43 ◽  
pp. 107-112 ◽  
Author(s):  
Gemma Leone ◽  
Marco Consumi ◽  
Claudia Franzi ◽  
Gabriella Tamasi ◽  
Stefania Lamponi ◽  
...  
Keyword(s):  
Inhibitory Activity ◽  
Coenzyme A ◽  
Hmg Coa Reductase ◽  
Liposomal Formulations ◽  
Coa Reductase

Eight new triterpenoids with inhibitory activity against HMG-CoA reductase from the medical mushroom Ganoderma leucocontextum collected in Tibetan plateau

Fitoterapia ◽  
2018 ◽  
Vol 130 ◽  
pp. 79-88 ◽  
Author(s):  
Jinjin Zhang ◽  
Ke Ma ◽  
Junjie Han ◽  
Kai Wang ◽  
Hongyu Chen ◽  
...  
Keyword(s):  
Tibetan Plateau ◽  
Inhibitory Activity ◽  
Hmg Coa Reductase ◽  
Coa Reductase

scholarly journals Penambatan molekul senyawa turunan orizanol terhadap enzim 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reduktase

2020 ◽  
Vol 4 (1) ◽  
pp. 43
Author(s):  
Syaikhul Aziz ◽  
Nur Adliani ◽  
Sukrasno Sukrasno
Keyword(s):  
Molecular Docking ◽  
Total Cholesterol ◽  
Protein Data Bank ◽  
Metabolic Pathway ◽  
Inhibitory Activity ◽  
Data Bank ◽  
Inhibition Activity ◽  
Hmg Coa Reductase ◽  
Hypolipidemic Agent ◽  
Coa Reductase

Oryzanol has been reported to reduce serum total cholesterol (hypolipidemic agent) by inhibiting HMG-CoA reductase, an enzyme responsible for the metabolic pathway that produces cholesterol and isoprenoid. The purpose of this experiment is to determine the inhibition activity of oryzanol derivatives on HMG-CoA reductase by molecular docking. Four structure of oryzanol derivatives, Lanosteryl-ferulate, Brassicasteryl-ferulate, Lupeol-ferulate, and Cholesteryl-ferulate were used as ligands for molecular docking. The HMG-CoA reductase structure was obtained from protein data bank and the study was performed using AutoDock Tools as a molecular docking software. All oryzanol derivatives show binding affinity against HMG-CoA reductase. Lupeol-ferulate was predicted to be the best inhibitory activity against HMG-CoA reductase because of molecular docking.

scholarly journals HMG-CoA Reductase Inhibitory Activity of Gnetum gnemon Seed Extract and Identification of Potential Inhibitors for Lowering Cholesterol Level

2017 ◽  
Vol 9 (4) ◽  
pp. 559-565 ◽  
Author(s):  
Kholid Abdul Hafidz ◽  
Nuraini Puspitasari ◽  
Azminah A ◽  
Arry Yanuar ◽  
Yuditya Artha ◽  
...  
Keyword(s):  
Cholesterol Level ◽  
Inhibitory Activity ◽  
Seed Extract ◽  
Hmg Coa Reductase ◽  
Gnetum Gnemon ◽  
Coa Reductase ◽  
Potential Inhibitors
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