<p>This talk will contrast how U.S. decision makers&#8217; impacts-focused perspective on compound extreme events differs from climate science-based perspectives. Examples from around the U.S. will be provided, with an emphasis on cascading impacts that have spanned multiple regions and sectors. The talk will also propose a path forward for synthesizing &#8216;top-down&#8217; and &#8216;bottom-up&#8217; approaches to compound extremes, to facilitate adaptation. Time-permitting, preliminary findings from an analysis of sequential humid heat and extreme precipitation over the U.S. may be shown, as a guiding example. The work described reflects a collaboration of scientists funded by NOAA&#8217;s Regional Integrated Sciences and Assessments (RISA) program, charged with co-generating &#8216;useable science&#8217; by working closely with stakeholders. &#160;&#160;</p>