Active fault is the most dangerous natural hazards of buried steel pipelines, as large stress and strain induced by ground movement can lead to pipe failure, which may cause severe accidents. Based on nonlinear finite element method, local buckling behavior of buried high strength X80 steel pipelines under compression strike-slip fault was studied systematically. Accuracy of the numerical model was validated by previous full scale experimental results. A baseline analysis was performed to elucidate the local buckling phenomenon of pipe. Parametric analysis was also performed to investigate the effects of influence factors of pipe’s buckling behavior. Results shows that, when local buckling occurs, axial section force decreases abruptly. When pipe-fault intersection angle equals 135°, the maximum axial section force peaks and the critical fault displacement is the smallest. With the increase of pipe wall thickness, the maximum axial section force and the critical fault displacement increases. With the increase of pipe internal pressure, the maximum axial section force and the critical fault displacement decreases. When p = 0MPa, inward-diamond buckling occurs in the pipe. While p≥4MPa, elephant-foot buckling occurs in the pipe.