Diagnostic conundrum of oppositional defiant disorder and conduct disorder.

1991 ◽  
Vol 100 (3) ◽  
pp. 379-390 ◽  
Author(s):  
Rolf Loeber ◽  
Benjamin B. Lahey ◽  
Christopher Thomas
2013 ◽  
Vol 44 (5) ◽  
pp. 1053-1064 ◽  
Author(s):  
V. S. Knopik ◽  
L. C. Bidwell ◽  
C. Flessner ◽  
N. Nugent ◽  
L. Swenson ◽  
...  

BackgroundDSM-IV specifies a hierarchal diagnostic structure such that an oppositional defiant disorder (ODD) diagnosis is applied only if criteria are not met for conduct disorder (CD). Genetic studies of ODD and CD support a combination of shared genetic and environmental influences but largely ignore the imposed diagnostic structure.MethodWe examined whether ODD and CD share an underlying etiology while accounting for DSM-IV diagnostic specifications. Data from 1446 female twin pairs, aged 11–19 years, were fitted to two-stage models adhering to the DSM-IV diagnostic hierarchy.ResultsThe models suggested that DSM-IV ODD–CD covariation is attributed largely to shared genetic influences.ConclusionsThis is the first study, to our knowledge, to examine genetic and environmental overlap among these disorders while maintaining a DSM-IV hierarchical structure. The findings reflect primarily shared genetic influences and specific (i.e. uncorrelated) shared/familial environmental effects on these DSM-IV-defined behaviors. These results have implications for how best to define CD and ODD for future genetically informed analyses.


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