The need for multi-modal and multi-functional measurement systems in laboratory animal research and matrix analysis

Laboratory Animal Research Centre (LARC) has developed an early emergency operational plan for COVID-19 pandemic situation. Biosafety and biosecurity measures were planned and implemented ahead of time to check the functional requirement to prevent the infection. Identified necessary support for IT, transport, procurement, finance, admin and research to make the operations remotely and successfully.

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Rapid Response by Laboratory Animal Research Institutions During the COVID-19 Pandemic: Lessons Learned

10.17226/26189 ◽

2021 ◽

Author(s):

◽

Keyword(s):

Laboratory Animal ◽

Animal Research ◽

Lessons Learned ◽

Rapid Response ◽

Research Institutions

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Biosecurity in laboratory animal research facilities.

Biosecurity in animal production and veterinary medicine: from principles to practice ◽

10.1079/9781789245684.0475 ◽

2019 ◽

pp. 475-495

Author(s):

P. H. Chen ◽

R. Trundy

Keyword(s):

Laboratory Animal ◽

Animal Research ◽

Research Facilities

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Putting the Ethical Principles into Practice

Principles of Animal Research Ethics ◽

10.1093/med/9780190939120.003.0004 ◽

2020 ◽

pp. 69-78

Author(s):

Rebecca Dresser

Keyword(s):

Policy Change ◽

Laboratory Animal ◽

Social Benefit ◽

Core Values ◽

Animal Research ◽

Scientific Quality ◽

Scientific Review ◽

Committee Membership ◽

Animal Use ◽

Research Studies

Beauchamp and DeGrazia introduce a framework of core values and principles for animal research studies that is more comprehensive than the leading alternative—Russell and Burch’s Three-Rs scheme of replacing, refining, and reducing laboratory animal use. Beauchamp and DeGrazia’s principles flesh out both social benefit requirements and animal welfare values. I recommend changes that would make their framework a real force in the conduct of animal research. One positive change would be a requirement to increase the diversity of institutional committee membership. A better scientific review system would substantially improve assessments of the justification of research studies. Existing government provisions on animal research direct committees to consider scientific quality but fail to provide the tools for doing so. Setting limits on the number of animals allowed in research is another needed policy change.

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