Opioid substitution treatment as HIV prevention among people who inject drugs: Focus on developing country settings

2012 ◽  
Author(s):  
Atul Ambekar
Keyword(s):  
Hiv Prevention ◽  
Developing Country ◽  
People Who Inject Drugs ◽  
Substitution Treatment ◽  
Opioid Substitution Treatment ◽  
Opioid Substitution

scholarly journals Opioid substitution treatment uptake among people who inject drugs: The findings of two consecutive bio-behavioral surveillance surveys in Iran

2020 ◽  
Author(s):  
Mehran Nakhaeizadeh ◽  
Zahra Abdolahiniya ◽  
Hamid Sharifi ◽  
Ali Mirzazadeh ◽  
Mohammad Karamouzian ◽  
...  
Keyword(s):  
Health Outcomes ◽  
Harm Reduction ◽  
People Who Inject Drugs ◽  
Substitution Treatment ◽  
Urban Centers ◽  
Opioid Substitution Treatment ◽  
Behavioral Surveillance ◽  
Opioid Drugs ◽  
History Of ◽  
Opioid Substitution

Abstract Background Opioid substitution treatment (OST) uptake has been associated with multiple positive health outcomes among people who inject drugs (PWID). This study evaluated the pattern of OST uptake among PWID in two consecutive national bio-behavioral surveillance surveys (2010 and 2014) in Iran. Methods Data were obtained from two national bio-behavioral surveillance surveys (N2010 = 1,783 and N2014 = 2,166) implemented using convenience sampling at the harm reduction facilities and street venues in 10 geographically diverse urban centers across Iran. Multivariable logistic regression model was used to determine the correlates of OST uptake for 2014 survey and adjusted odds ratios (AORs) and 95% confidence intervals (CI) were reported. Results The prevalence of OST uptake decreased from 49.2% in 2010 to 45.8% in 2014 (P-value = 0.033). OST uptake varied across the studied cities ranging from 0.0%-69.3% in the 2010 survey and 3.2%-75.5% in the 2014 survey. Ever being married (AOR = 1.40; 95% CI: 1.12, 1.75), having a history of incarceration (AOR = 1.56; 95% CI: 1.16, 2.09), and human immunodeficiency virus (HIV) sero-positivity (AOR = 1.63; 95% CI: 1.08, 2.5) were associated with OST uptake. Conversely, PWID who reported using only non-opioid drugs (AOR = 0.43; 95% CI: 0.26, 0.71) and those who reported concurrent use of opioid and non-opioid drugs (AOR = 0.66; 95% CI: 0. 0.51, 0.86) were less likely to uptake OST. Conclusions Although OST uptake among PWID in Iran is above the 40% threshold defined by the World Health Organization, there remains significant disparities across urban centers in Iran. Importantly, the OST services appear to be serving high risk PWID including those living with HIV and those with a history of incarceration. Evaluating service integration including mental health, HIV and hepatitis C virus care, and other harm reduction services may support the optimization of health outcomes of opioid substitution treatment across Iran.

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