In this chapter, the author looks at compassion from two psychological perspectives: evolutionary and developmental. Evolutionary psychology proposes that there are three emotion systems: threat/self-protect, drive/reward, and affiliative/soothing. By developing our capacity to mindfully access, accept, and direct affiliative motives and emotions—for others and ourselves—we can cultivate compassion skills to shift our mind toward the affiliative/soothing system and down-regulate the threat/self-protect and drive/reward systems. Developmental psychology further contributes to our understanding of compassion by proposing two behavioural systems: the attachment behavioural system that governs support-seeking and the caregiving behavioural system that governs support provision. It suggests that the interplay between these two systems may account for individual differences in the disposition to compassion. Last, the author shows that compassion not only benefits the recipients, but also improves the psychological health of the caregivers.