Simian virus 40 facilitates multiplication of replication defective mutants of polyoma virus in BALB/3T3 mouse cells

Nature ◽  
1977 ◽  
Vol 267 (5611) ◽  
pp. 528-529 ◽  
Author(s):  
AKIRA HAKURA
Keyword(s):  
Simian Virus 40 ◽  
Simian Virus ◽  
Polyoma Virus ◽  
Mouse Cells

scholarly journals Simian virus 40 and polyoma virus induce synthesis of heat shock proteins in permissive cells.

1983 ◽  
Vol 3 (1) ◽  
pp. 1-8 ◽  
Author(s):  
E W Khandjian ◽  
H Türler
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Gel Electrophoresis ◽  
Mammalian Cells ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
Polyoma Virus ◽  
Two Dimensional Gel Electrophoresis ◽  
Mouse Cells ◽  
Stimulation Of

During the lytic infection of monkey and mouse cells with simian virus 40 and polyoma virus, respectively, the preferentially increased synthesis of two host proteins of 92,000 and 72,000 Mr was observed by 15 to 20 h after infection besides the general stimulation of most cellular proteins. The incubation of uninfected monkey and mouse cell cultures for 30 to 60 min at 43.5 degrees C induced the enhanced synthesis of at least three proteins of 92,000, 72,000 and 70,000 Mr, the last one being the major heat shock protein of mammalian cells. Two-dimensional gel electrophoresis and partial proteolytic digestion confirmed that the same 92,000- and 72,000-Mr proteins are stimulated by virus infection and thermal treatment. In simian virus 40-infected CV-1 cells, we also observed the weak stimulation of a 70,000-Mr protein comigrating in gel electrophoresis with the major heat shock protein. The 92,000-, 72,000- and 70,000-Mr proteins of monkey cells are structurally very similar to the corresponding proteins of mouse cells. In immunoprecipitations, no specific association of these proteins to simian virus 40 T antigens was noticed.

Simian virus 40 and polyoma virus induce synthesis of heat shock proteins in permissive cells

1983 ◽  
Vol 3 (1) ◽  
pp. 1-8
Author(s):  
E W Khandjian ◽  
H Türler
Keyword(s):  
Heat Shock ◽  
Heat Shock Protein ◽  
Gel Electrophoresis ◽  
Mammalian Cells ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
Polyoma Virus ◽  
Two Dimensional Gel Electrophoresis ◽  
Mouse Cells ◽  
Stimulation Of

During the lytic infection of monkey and mouse cells with simian virus 40 and polyoma virus, respectively, the preferentially increased synthesis of two host proteins of 92,000 and 72,000 Mr was observed by 15 to 20 h after infection besides the general stimulation of most cellular proteins. The incubation of uninfected monkey and mouse cell cultures for 30 to 60 min at 43.5 degrees C induced the enhanced synthesis of at least three proteins of 92,000, 72,000 and 70,000 Mr, the last one being the major heat shock protein of mammalian cells. Two-dimensional gel electrophoresis and partial proteolytic digestion confirmed that the same 92,000- and 72,000-Mr proteins are stimulated by virus infection and thermal treatment. In simian virus 40-infected CV-1 cells, we also observed the weak stimulation of a 70,000-Mr protein comigrating in gel electrophoresis with the major heat shock protein. The 92,000-, 72,000- and 70,000-Mr proteins of monkey cells are structurally very similar to the corresponding proteins of mouse cells. In immunoprecipitations, no specific association of these proteins to simian virus 40 T antigens was noticed.

Ability of nonpermissive mouse cells to express a simian virus 40 late function(s).

1981 ◽  
Vol 38 (3) ◽  
pp. 940-951 ◽  
Author(s):  
M Lange ◽  
E May ◽  
P May
Keyword(s):  
Simian Virus 40 ◽  
Simian Virus ◽  
Mouse Cells ◽  
Late Function

scholarly journals Nonselective expression of simian virus 40 large tumor antigen fragments in mouse cells.

1982 ◽  
Vol 79 (6) ◽  
pp. 2064-2067 ◽  
Author(s):  
V. B. Reddy ◽  
S. S. Tevethia ◽  
M. J. Tevethia ◽  
S. M. Weissman
Keyword(s):  
Tumor Antigen ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
Large Tumor ◽  
Large Tumor Antigen ◽  
Mouse Cells

scholarly journals In vivo competition of delta-crystallin gene expression by DNA fragments containing a GC box.

1986 ◽  
Vol 6 (11) ◽  
pp. 4130-4132 ◽  
Author(s):  
S Hayashi ◽  
H Kondoh
Keyword(s):  
Gene Expression ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
Dna Fragments ◽  
Specific Expression ◽  
Mouse Cells ◽  
Gc Box ◽  
Simplex Virus

Expression of the chicken delta-crystallin gene 1 injected into the nuclei of mouse cells is lens specific. Coinjection of GC box-containing DNA fragments from delta-crystallin, simian virus 40 early, and herpes simplex virus type 1 tk promoters effectively suppressed delta-crystallin expression in the lens, but coinjection with DNA fragments not containing the GC box did not. This suppression was likely due to the competition of an Sp1-like transcription factor(s) and indicates involvement of the apparently ubiquitous factor(s) in the tissue-specific expression of the delta-crystallin gene.

scholarly journals Lack of Sequence Homology Between the 70S RNA of Various RNA Tumor Viruses and the DNA of Simian Virus 40 or Polyoma Virus

1973 ◽  
Vol 11 (6) ◽  
pp. 1027-1029
Author(s):  
Robert E. Gallagher ◽  
Arthur S. Levine ◽  
David H. Gillespie ◽  
Robert C. Gallo
Keyword(s):  
Sequence Homology ◽  
Simian Virus 40 ◽  
Simian Virus ◽  
Polyoma Virus ◽  
Tumor Viruses ◽  
Rna Tumor Viruses

Biology of simian virus 40 (SV40) transplantation antigen (TrAg) VII. Induction of SV40 TrAg in nonpermissive mouse cells by early viable SV40 deletion (0.54/0.59) mutants

Virology ◽  
1980 ◽  
Vol 107 (2) ◽  
pp. 488-496 ◽  
Author(s):  
Satvir S. Tevethia ◽  
David C. Flyer ◽  
Mary J. Tevethia ◽  
William C. Topp
Keyword(s):  
Simian Virus 40 ◽  
Simian Virus ◽  
Transplantation Antigen ◽  
Mouse Cells
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