Identification and in vitro pharmacological characterization of a novel and selective α7 nicotinic acetylcholine receptor agonist, Br-IQ17B

Receptor Agonist ◽

In Vitro Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.167072 ◽

2010 ◽

Vol 334 (3) ◽

pp. 863-874 ◽

Cited By ~ 40

Author(s):

John Malysz ◽

David J. Anderson ◽

Jens H. Grønlien ◽

Jianguo Ji ◽

William H. Bunnelle ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Synthesis and Pharmacological Characterization of Novel Analogues of the Nicotinic Acetylcholine Receptor Agonist (±)-UB-165

Journal of Medicinal Chemistry ◽

10.1021/jm020814l ◽

2002 ◽

Vol 45 (15) ◽

pp. 3235-3245 ◽

Cited By ~ 33

Author(s):

Christopher G. V. Sharples ◽

Gunter Karig ◽

Graham L. Simpson ◽

James A. Spencer ◽

Emma Wright ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist

Brain Research ◽

10.1016/j.brainres.2008.07.063 ◽

2008 ◽

Vol 1234 ◽

pp. 16-24 ◽

Cited By ~ 5

Author(s):

Tadimeti S. Rao ◽

Pamala B. Adams ◽

Lucia D. Correa ◽

Emily M. Santori ◽

Aida I. Sacaan ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

Concentration-response relationship of the α7 nicotinic acetylcholine receptor agonist FRM-17874 across multiple in vitro and in vivo assays

Biochemical Pharmacology ◽

10.1016/j.bcp.2015.07.006 ◽

2015 ◽

Vol 97 (4) ◽

pp. 576-589 ◽

Cited By ~ 19

Author(s):

Milan Stoiljkovic ◽

Liza Leventhal ◽

Angela Chen ◽

Ting Chen ◽

Rachelle Driscoll ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

Response Relationship ◽

Nicotinic Acetylcholine ◽

In Vivo Assays ◽

Relationship Of

In Vivo Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107: Preclinical Considerations in Alzheimer's Disease

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.167213 ◽

2010 ◽

Vol 334 (3) ◽

pp. 875-886 ◽

Cited By ~ 74

Author(s):

R. Scott Bitner ◽

William H. Bunnelle ◽

Michael W. Decker ◽

Karla U. Drescher ◽

Kathy L. Kohlhaas ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

In vitro pharmacological characterization of (±)-4-[2-(1-methyl-2-pyrrolidinyl)ethyl]thio]phenol hydrochloride (SIB-1553A), a nicotinic acetylcholine receptor ligand

Brain Research ◽

10.1016/s0006-8993(03)02979-2 ◽

2003 ◽

Vol 981 (1-2) ◽

pp. 85-98 ◽

Cited By ~ 15

Author(s):

Tadimeti S. Rao ◽

Pamala B. Adams ◽

Lucia D. Correa ◽

Emily M. Santori ◽

Aida I. Sacaan ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Ligand ◽

Pharmacological Characterization of the Novel and Selective α7 Nicotinic Acetylcholine Receptor–Positive Allosteric Modulator BNC375

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.119.263483 ◽

2020 ◽

Vol 373 (2) ◽

pp. 311-324 ◽

Cited By ~ 2

Author(s):

Xiaohai Wang ◽

Christopher Daley ◽

Vanita Gakhar ◽

Henry S. Lange ◽

Joshua D. Vardigan ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Allosteric Modulator ◽

The Novel ◽

Positive Allosteric Modulator ◽

In vivo and in vitro ADMET profiling and in vivo pharmacodynamic investigations of a selective α7 nicotinic acetylcholine receptor agonist with a spirocyclic Δ 2 -isoxazoline molecular skeleton

European Journal of Pharmacology ◽

10.1016/j.ejphar.2017.12.047 ◽

2018 ◽

Vol 820 ◽

pp. 265-273 ◽

Cited By ~ 3

Author(s):

Carlo Matera ◽

Giulio Dondio ◽

Daniela Braida ◽

Luisa Ponzoni ◽

Marco De Amici ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Receptor Agonist ◽

Nicotinic Acetylcholine ◽

Molecular Skeleton

P4-310: Preclinical characterization of a selective alpha-7 neuronal nicotinic acetylcholine receptor agonist ABT-126: A novel therapeutic agent for the treatment of cognitive impairment in Alzheimer's disease and schizophrenia

Alzheimer s & Dementia ◽

10.1016/j.jalz.2013.05.1755 ◽

2013 ◽

Vol 9 ◽

pp. P817-P818 ◽

Cited By ~ 5

Author(s):

Robert Bitner ◽

David Anderson ◽

Karla Drescher ◽

Kathy Kohlhaas ◽

Halvard Gronlien ◽

...

Keyword(s):

Cognitive Impairment ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Therapeutic Agent ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Alpha 7 ◽

Novel Therapeutic

Efficacy and Safety of the α7-Nicotinic Acetylcholine Receptor Agonist ABT-126 in the Treatment of Cognitive Impairment Associated With Schizophrenia

The Journal of Clinical Psychiatry ◽

10.4088/jcp.16m11162 ◽

2018 ◽

Vol 79 (3) ◽

Cited By ~ 3

Author(s):

George M. Haig ◽

Deli Wang ◽

Jun Zhao ◽

Ahmed A. Othman ◽

Earle E. Bain

Keyword(s):

Cognitive Impairment ◽

Acetylcholine Receptor ◽

Receptor Agonist ◽

Efficacy And Safety ◽