Synthesis and Pharmacological Characterization of Novel Analogues of the Nicotinic Acetylcholine Receptor Agonist (±)-UB-165

Journal of Medicinal Chemistry ◽

10.1021/jm020814l ◽

2002 ◽

Vol 45 (15) ◽

pp. 3235-3245 ◽

Author(s):

Christopher G. V. Sharples ◽

Gunter Karig ◽

Graham L. Simpson ◽

James A. Spencer ◽

Emma Wright ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine

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In Vitro Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.167072 ◽

2010 ◽

Vol 334 (3) ◽

pp. 863-874 ◽

Author(s):

John Malysz ◽

David J. Anderson ◽

Jens H. Grønlien ◽

Jianguo Ji ◽

William H. Bunnelle ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine

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Pharmacological characterization of (S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), a novel nicotinic acetylcholine receptor agonist

Brain Research ◽

10.1016/j.brainres.2008.07.063 ◽

2008 ◽

Vol 1234 ◽

pp. 16-24 ◽

Author(s):

Tadimeti S. Rao ◽

Pamala B. Adams ◽

Lucia D. Correa ◽

Emily M. Santori ◽

Aida I. Sacaan ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine

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In Vivo Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107: Preclinical Considerations in Alzheimer's Disease

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.167213 ◽

2010 ◽

Vol 334 (3) ◽

pp. 875-886 ◽

Author(s):

R. Scott Bitner ◽

William H. Bunnelle ◽

Michael W. Decker ◽

Karla U. Drescher ◽

Kathy L. Kohlhaas ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine

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Identification and in vitro pharmacological characterization of a novel and selective α7 nicotinic acetylcholine receptor agonist, Br-IQ17B

Acta Pharmacologica Sinica ◽

10.1038/aps.2015.9 ◽

2015 ◽

Vol 36 (7) ◽

pp. 800-812 ◽

Author(s):

Jing-shu Tang ◽

Bing-xue Xie ◽

Xi-ling Bian ◽

Yu Xue ◽

Ning-ning Wei ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine

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P4-310: Preclinical characterization of a selective alpha-7 neuronal nicotinic acetylcholine receptor agonist ABT-126: A novel therapeutic agent for the treatment of cognitive impairment in Alzheimer's disease and schizophrenia

Alzheimer s & Dementia ◽

10.1016/j.jalz.2013.05.1755 ◽

2013 ◽

Vol 9 ◽

pp. P817-P818 ◽

Author(s):

Robert Bitner ◽

David Anderson ◽

Karla Drescher ◽

Kathy Kohlhaas ◽

Halvard Gronlien ◽

...

Keyword(s):

Cognitive Impairment ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Therapeutic Agent ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Alpha 7 ◽

Novel Therapeutic

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Pharmacological characterization of nicotinic acetylcholine receptor (nACh-R)-mediated acetylcholine release in rat brain - in vivo microdialysis study

The Japanese Journal of Pharmacology ◽

10.1016/s0021-5198(19)44859-2 ◽

1997 ◽

Vol 73 ◽

pp. 88

Author(s):

Yoshihiro Tani ◽

Kyoshi Saito ◽

Masahiro Imoto ◽

Tomochika Ohno

Keyword(s):

Rat Brain ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Acetylcholine Release ◽

In Vivo Microdialysis ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine ◽

Microdialysis Study

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Pharmacological Characterization of the Allosteric Modulator Desformylflustrabromine and Its Interaction with α4β2 Neuronal Nicotinic Acetylcholine Receptor Orthosteric Ligands

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.167684 ◽

2010 ◽

Vol 334 (3) ◽

pp. 917-926 ◽

Author(s):

Maegan M. Weltzin ◽

Marvin K. Schulte

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Allosteric Modulator ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine ◽

Orthosteric Ligands

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Pharmacological characterization of dopamine, norepinephrine and serotonin release in the rat prefrontal cortex by neuronal nicotinic acetylcholine receptor agonists

Brain Research ◽

10.1016/s0006-8993(03)03532-7 ◽

2003 ◽

Vol 990 (1-2) ◽

pp. 203-208 ◽

Author(s):

Tadimeti S. Rao ◽

Lucia D. Correa ◽

Pamala Adams ◽

Emily M. Santori ◽

Aida I. Sacaan

Keyword(s):

Prefrontal Cortex ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Serotonin Release ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine ◽

Receptor Agonists

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The Expression and Pharmacological Characterization of Nicotinic Acetylcholine Receptor Subunits in HBE16 Airway Epithelial Cells

Cell Biochemistry and Biophysics ◽

10.1007/s12013-011-9324-z ◽

2011 ◽

Vol 62 (3) ◽

pp. 421-431 ◽

Author(s):

Qi Li ◽

Xiangdong Zhou ◽

Victor P. Kolosov ◽

Juliy M. Perelman

Keyword(s):

Epithelial Cells ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Airway Epithelial Cells ◽

Airway Epithelial ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine

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Chemistry and Pharmacological Characterization of Novel Nitrogen Analogues of AMOP-H-OH (Sazetidine-A, 6-[5-(Azetidin-2-ylmethoxy)pyridin-3-yl]hex-5-yn-1-ol) as α4β2-Nicotinic Acetylcholine Receptor-Selective Partial Agonists

Journal of Medicinal Chemistry ◽

10.1021/jm100765u ◽

2010 ◽

Vol 53 (19) ◽

pp. 6973-6985 ◽

Author(s):

Jianhua Liu ◽

J. Brek Eaton ◽

Barbara Caldarone ◽

Ronald J. Lukas ◽

Alan P. Kozikowski

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine ◽

Partial Agonists ◽

Nitrogen Analogues

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