scholarly journals Evaluating linkage disequilibrium and recombination provides a haplotype-tagging SNP panel of the major histocompatibility complex in African Americans

2008 ◽  
Vol 9 (3) ◽  
pp. 271-273 ◽  
Author(s):  
J M Kelley ◽  
L B Hughes ◽  
R Feng ◽  
N Liu ◽  
M A Padilla ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Linkage Disequilibrium ◽  
African Americans ◽  
Major Histocompatibility ◽  
Tagging Snp ◽  
Histocompatibility Complex ◽  
Snp Panel

Major histocompatibility complex class II haplotypes and linkage disequilibrium values observed in the CEPH families

1994 ◽  
Vol 41 (3) ◽  
pp. 234-240 ◽  
Author(s):  
Mary Carrington ◽  
J Claiborne Stephens ◽  
William Klitz ◽  
Ann B Begovich ◽  
Henry A Erlich ◽  
...  
Keyword(s):  
Major Histocompatibility Complex ◽  
Linkage Disequilibrium ◽  
Major Histocompatibility Complex Class ◽  
Class Ii ◽  
Complex Class ◽  
Major Histocompatibility ◽  
Histocompatibility Complex

scholarly journals Association of low C2 and C4 serum levels with the HLA-DW2 allele in healthy individuals.

1978 ◽  
Vol 148 (3) ◽  
pp. 704-713 ◽  
Author(s):  
C Nerl ◽  
H Grosse-Wilde ◽  
G Valet
Keyword(s):  
Major Histocompatibility Complex ◽  
Linkage Disequilibrium ◽  
Serum Protein ◽  
Functional Activity ◽  
Serum Levels ◽  
Bimodal Distribution ◽  
Major Histocompatibility ◽  
Healthy Individuals ◽  
Protein Levels ◽  
Histocompatibility Complex

HLA typed unrelated healthy individuals (HLA-DW2 positive n = 64, and HLA-DW2 negative n = 72) were investigated for their C2 functional activity and C4 serum protein levels. For the C2 and C4 levels a bimodal distribution was found in HLA-DW2 positive and HLA-DW2 negative individuals. HLA-DW2 positive persons had a significantly higher incidence of low C2 and C4 serum levels. Our data support the concept that genes governing C2 as well as C4 serum levels are in linkage disequilibrium with the HLA-DW2 allele of the major histocompatibility complex.

Absence of strong linkage disequilibrium between odorant receptor alleles and the major histocompatibility complex

2013 ◽  
Vol 74 (12) ◽  
pp. 1619-1623
Author(s):  
José Samuel da Silva ◽  
Pryscilla Fanini Wowk ◽  
Fabiana Poerner ◽  
Pablo Sandro Carvalho Santos ◽  
Maria da Graça Bicalho
Keyword(s):  
Major Histocompatibility Complex ◽  
Linkage Disequilibrium ◽  
Odorant Receptor ◽  
Strong Linkage Disequilibrium ◽  
Major Histocompatibility ◽  
Strong Linkage ◽  
Histocompatibility Complex
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