scholarly journals Inheritance of the Bantu/Benin haplotype causes less severe hemolytic and oxidative stress in sickle cell anemia patients treated with hydroxycarbamide

2016 ◽  
Vol 61 (7) ◽  
pp. 605-611 ◽  
Author(s):  
Jéssika V Okumura ◽  
Danilo G H Silva ◽  
Lidiane S Torres ◽  
Edis Belini-Junior ◽  
Willian M Barberino ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
And Oxidative Stress

scholarly journals Relationship between adenosine deaminase polymorphism (c.22G > A) and oxidative stress in sickle cell anemia

Meta Gene ◽  
2017 ◽  
Vol 11 ◽  
pp. 172-177
Author(s):  
Danilo Grünig Humberto da Silva ◽  
Edis Belini-Junior ◽  
Lidiane de Souza Torres ◽  
Jessika Viviani Okumura ◽  
Willian Marcel Barberino ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Adenosine Deaminase ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
And Oxidative Stress

scholarly journals Energy Expenditure, Inflammation, and Oxidative Stress in Steady-State Adolescents With Sickle Cell Anemia

2007 ◽  
Vol 61 (2) ◽  
pp. 233-238 ◽  
Author(s):  
Sylvie A Akohoue ◽  
Sadhna Shankar ◽  
Ginger L Milne ◽  
Jason Morrow ◽  
Kong Y Chen ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Steady State ◽  
Energy Expenditure ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
And Oxidative Stress

Serum melatonin level and oxidative stress in sickle cell anemia

2010 ◽  
Vol 45 (4) ◽  
pp. 297-301 ◽  
Author(s):  
Eliana Litsuko Tomimatsu Shimauti ◽  
Danilo Grunig Humberto Silva ◽  
Eduardo Alves de Almeida ◽  
Paula Juliana Antoniazzo Zamaro ◽  
Edis Belini Junior ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Melatonin Level ◽  
And Oxidative Stress

scholarly journals Impact of iron overload on interleukin-10 levels, biochemical parameters and oxidative stress in patients with sickle cell anemia

2013 ◽  
Vol 35 (1) ◽  
pp. 29-34 ◽  
Author(s):  
Maritza Cavalcante Barbosa ◽  
Talyta Ellen Jesus dos Santos ◽  
Geane Félix de Souza ◽  
Lívia Coêlho de Assis ◽  
Max Victor Carioca Freitas ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Iron Overload ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Biochemical Parameters ◽  
Interleukin 10 ◽  
And Oxidative Stress

scholarly journals Relationship between Higher Atherogenic Index of Plasma and Oxidative Stress of a Group of Patients Living with Sickle Cell Anemia in Cameroon

2020 ◽  
Vol 2020 ◽  
pp. 1-7 ◽  
Author(s):  
Landry Nguepnkep Kubong ◽  
Prosper Cabral Nya Biapa ◽  
Bernard Chetcha ◽  
Nicolas Yanou-Njintang ◽  
Vicky Jocelyne Moor Ama ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Lipid Profile ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Low Density Lipoprotein ◽  
Density Lipoprotein ◽  
Atherogenic Index ◽  
Atherogenic Index Of Plasma ◽  
Spectrophotometric Methods ◽  
And Oxidative Stress

Dyslipidemia is highly prevalent in sickle cell anemia (SCA) patients and is one of the major risk factors for cardiovascular diseases induced by oxidative stress in Africa. The aim of this research was to investigate the correlation between higher atherogenic index of plasma (API) and oxidative stress in a group of patients living with SCA in Cameroon. Methods. A group of 85 homozygote SS patients (male and female) were enrolled at the Central hospital of Yaounde in Cameroon between May and October 2017. After informed consent through the signature of a consent form was obtained, the plasma was collected to determine the lipid profile while the lysate solution of RBC was used to explore some markers of oxidative stress using spectrophotometric methods. Results. Among the 85 patients included in our study, the mean age was 30 ± 5 years and the female to male ratio was 0.97. The majority of the patients (52–81%) had dyslipidaemia, and 22.4% of the patients demonstrated a higher level of atherogenic index of plasma. The patients with a higher level of total cholesterol (TC) (>240 mg/dl) and low-density lipoprotein (LDL-C) (>159 mg/dl) had at least 1,334 fold of malondialdeheyde (MDA) concentration than those with normal level. Also in the same patients, the higher atherogenic plasmatic index (API) significantly (p<0.05) increased with the concentration of MDA. Except HDL-C, the other parameters of lipid profile had significant (p<0.05) correlation with reduced glutathione (GsH) and total antioxidant capacity (TAC). The significant (p<0.05) and linear regression was found between the increased MDA and higher API. Conclusion. Dyslipidemia increases oxidative stress and higher API which leads to coronary vascular disease in patients with SCA.

scholarly journals The influence of hydroxyurea on oxidative stress in sickle cell anemia

2012 ◽  
Vol 34 (6) ◽  
pp. 421-425
Author(s):  
Lidiane de Souza Torres<sup></sup> ◽  
Danilo Grünig Humberto da Silva<sup></sup> ◽  
Edis Belini Junior<sup></sup> ◽  
Eduardo Alves de Almeida<sup></sup> ◽  
Clarisse Lopes de Castro Lobo<sup></sup> ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Sickle Cell ◽  
Sickle Cell Anemia

Association between Oxidative Stress, Genetic Factors, and Clinical Severity in Children with Sickle Cell Anemia

2018 ◽  
Vol 195 ◽  
pp. 228-235 ◽  
Author(s):  
Céline Renoux ◽  
Philippe Joly ◽  
Camille Faes ◽  
Pauline Mury ◽  
Buse Eglenen ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Sickle Cell ◽  
Sickle Cell Anemia ◽  
Genetic Factors ◽  
Clinical Severity
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