scholarly journals Structure of the proton-gated urea channel from the gastric pathogen Helicobacter pylori

Nature ◽  
2012 ◽  
Vol 493 (7431) ◽  
pp. 255-258 ◽  
Author(s):  
David Strugatsky ◽  
Reginald McNulty ◽  
Keith Munson ◽  
Chiung-Kuang Chen ◽  
S. Michael Soltis ◽  
...  

2007 ◽  
Vol 7 (4) ◽  
pp. 463-468 ◽  
Author(s):  
Niyaz Ahmed ◽  
Ahmed A. Majeed ◽  
Irshad Ahmed ◽  
M. Abid Hussain ◽  
Ayesha Alvi ◽  
...  




Physiology ◽  
2005 ◽  
Vol 20 (6) ◽  
pp. 429-438 ◽  
Author(s):  
George Sachs ◽  
David L. Weeks ◽  
Yi Wen ◽  
Elizabeth A. Marcus ◽  
David R. Scott ◽  
...  

Helicobacter pylori is a Gram-negative neutralophile associated with peptic ulcers and gastric cancer. It has a unique ability to colonize the human stomach by acid acclimation. It uses the pH-gated urea channel, UreI, to enhance urea access to intrabacterial urease and a membrane-anchored periplasmic carbonic anhydrase to regulate periplasmic pH to ~6.1 in acidic media, whereas other neutralophiles cannot regulate periplasmic pH and thus only transit the stomach.



Nature ◽  
10.1038/41483 ◽  
1997 ◽  
Vol 388 (6642) ◽  
pp. 539-547 ◽  
Author(s):  
Jean-F. Tomb ◽  
Owen White ◽  
Anthony R. Kerlavage ◽  
Rebecca A. Clayton ◽  
Granger G. Sutton ◽  
...  


Nature ◽  
10.1038/16495 ◽  
1999 ◽  
Vol 397 (6715) ◽  
pp. 176-180 ◽  
Author(s):  
Richard A. Alm ◽  
Lo-See L. Ling ◽  
Donald T. Moir ◽  
Benjamin L. King ◽  
Eric D. Brown ◽  
...  


2015 ◽  
Vol 126 ◽  
pp. 34-45 ◽  
Author(s):  
Stephan A. Müller ◽  
Sandy R. Pernitzsch ◽  
Sven-Bastiaan Haange ◽  
Peter Uetz ◽  
Martin von Bergen ◽  
...  


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