IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination

M M Chitnis; K A Lodhia; T Aleksic; S Gao; A S Protheroe; V M Macaulay

doi:10.1038/onc.2013.460

IGF-1R inhibition enhances radiosensitivity and delays double-strand break repair by both non-homologous end-joining and homologous recombination

Oncogene ◽

10.1038/onc.2013.460 ◽

2013 ◽

Vol 33 (45) ◽

pp. 5262-5273 ◽

Cited By ~ 49

Author(s):

M M Chitnis ◽

K A Lodhia ◽

T Aleksic ◽

S Gao ◽

A S Protheroe ◽

...

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Break Repair ◽

Non Homologous End Joining

Abstract P2-05-08: Integrin alpha6beta4 signaling switches double strand break repair from homologous recombination to non-homologous end joining to alter TNBC cells response to cisplatin

10.1158/1538-7445.sabcs19-p2-05-08 ◽

2020 ◽

Author(s):

Min Chen ◽

Brock Marrs ◽

Lei Qi ◽

Teresa Knifley ◽

Stuart G Jarrett ◽

...

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Integrin Alpha6beta4 ◽

Break Repair ◽

Non Homologous End Joining

158 Double strand break repair in mammalian cells: competition between homologous recombination and non-homologous end joining through cell cycle

Radiotherapy and Oncology ◽

10.1016/s0167-8140(04)82025-5 ◽

2004 ◽

Vol 73 ◽

pp. S73-S74

Keyword(s):

Cell Cycle ◽

Homologous Recombination ◽

Mammalian Cells ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Break Repair ◽

Non Homologous End Joining

Abstract 1352: Inactivation of factors of DNA double-strand break repair by homologous recombination or non-homologous end-joining leads to frequent catastrophic genomic events in murine and human tumors

10.1158/1538-7445.am2018-1352 ◽

2018 ◽

Author(s):

Manasi Ratnaparkhe ◽

John Wong ◽

Pei-Chi Wei ◽

Mario Hlevnjak ◽

Paul Northcott ◽

...

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Human Tumors ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

Impairment of the non-homologous end joining and homologous recombination pathways of DNA double strand break repair: Impact on spontaneous and radiation-induced mammary and intestinal tumour risk in Apc mice

DNA Repair ◽

10.1016/j.dnarep.2015.08.002 ◽

2015 ◽

Vol 35 ◽

pp. 19-26 ◽

Cited By ~ 5

Author(s):

Jackie W. Haines ◽

Margaret Coster ◽

Simon D. Bouffler

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Intestinal Tumour ◽

Radiation Induced ◽

Break Repair ◽

Non Homologous End Joining

Differential usage of non-homologous end-joining and homologous recombination in double strand break repair

DNA Repair ◽

10.1016/j.dnarep.2006.05.022 ◽

2006 ◽

Vol 5 (9-10) ◽

pp. 1021-1029 ◽

Cited By ~ 329

Author(s):

Eiichiro Sonoda ◽

Helfrid Hochegger ◽

Alihossein Saberi ◽

Yoshihito Taniguchi ◽

Shunichi Takeda

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Break Repair ◽

Non Homologous End Joining

Inhibition of homologous recombination by hyperthermia shunts early double strand break repair to non-homologous end-joining

DNA Repair ◽

10.1016/j.dnarep.2012.10.008 ◽

2013 ◽

Vol 12 (1) ◽

pp. 38-45 ◽

Cited By ~ 30

Author(s):

Judith W.J. Bergs ◽

Przemek M. Krawczyk ◽

Tijana Borovski ◽

Rosemarie ten Cate ◽

Hans M. Rodermond ◽

...

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Break Repair ◽

Non Homologous End Joining

Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells

The EMBO Journal ◽

10.1093/emboj/17.18.5497 ◽

1998 ◽

Vol 17 (18) ◽

pp. 5497-5508 ◽

Cited By ~ 766

Author(s):

Minoru Takata ◽

Masao S. Sasaki ◽

Eiichiro Sonoda ◽

Ciaran Morrison ◽

Mitsumasa Hashimoto ◽

...

Keyword(s):

Homologous Recombination ◽

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

Mechanism of Double-Strand Break Repair by Non-Homologous End Joining

DNA Repair and Replication ◽

10.1201/9780429464744-7 ◽

2018 ◽

pp. 113-133

Author(s):

Michal Malewicz

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Break Repair ◽

Non Homologous End Joining

End-processing nucleases and phosphodiesterases: An elite supporting cast for the non-homologous end joining pathway of DNA double-strand break repair

DNA Repair ◽

10.1016/j.dnarep.2016.05.011 ◽

2016 ◽

Vol 43 ◽

pp. 57-68 ◽

Cited By ~ 24

Author(s):

Vijay Menon ◽

Lawrence F. Povirk

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Dna Double Strand Break ◽

Break Repair ◽

Non Homologous End Joining

Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining

The EMBO Journal ◽

10.1093/emboj/21.11.2827 ◽

2002 ◽

Vol 21 (11) ◽

pp. 2827-2832 ◽

Cited By ~ 168

Author(s):

C. Chappell

Keyword(s):

Strand Break ◽

Double Strand Break ◽

Double Strand Break Repair ◽

End Joining ◽

Polynucleotide Kinase ◽

Break Repair ◽

Non Homologous End Joining