scholarly journals Repertoire-scale determination of class II MHC peptide binding via yeast display improves antigen prediction

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
C. Garrett Rappazzo ◽  
Brooke D. Huisman ◽  
Michael E. Birnbaum
Keyword(s):  
Peptide Binding ◽  
Class Ii ◽  
Yeast Display ◽  
Class Ii Mhc

scholarly journals Citrullination only infrequently impacts peptide binding to HLA class II MHC

PLoS ONE ◽  
2017 ◽  
Vol 12 (5) ◽  
pp. e0177140 ◽  
Author(s):  
John Sidney ◽  
Stephane Becart ◽  
Mimi Zhou ◽  
Karen Duffy ◽  
Mikaela Lindvall ◽  
...  
Keyword(s):  
Peptide Binding ◽  
Class Ii ◽  
Hla Class Ii ◽  
Class Ii Mhc

scholarly journals A Polymorphic Pocket at the P10 Position Contributes to Peptide Binding Specificity in Class II MHC Proteins

2004 ◽  
Vol 11 (10) ◽  
pp. 1395-1402 ◽  
Author(s):  
Zarixia Zavala-Ruiz ◽  
Iwona Strug ◽  
Matthew W. Anderson ◽  
Jack Gorski ◽  
Lawrence J. Stern
Keyword(s):  
Peptide Binding ◽  
Binding Specificity ◽  
Class Ii ◽  
Peptide Binding Specificity ◽  
Class Ii Mhc

Invariant Chain Dissociation from Class II MHC Is a Catalyst for Foreign Peptide Binding

1994 ◽  
Vol 730 (1 Microbial Pat) ◽  
pp. 338-341 ◽  
Author(s):  
V. E. REYES ◽  
M. DAIBATA ◽  
R. ESPEJO ◽  
R. E. HUMPHREYS
Keyword(s):  
Peptide Binding ◽  
Class Ii ◽  
Invariant Chain ◽  
Foreign Peptide ◽  
Class Ii Mhc

Peptide binding by class I and class II MHC molecules

Biopolymers ◽  
1997 ◽  
Vol 43 (4) ◽  
pp. 281-302 ◽  
Author(s):  
Michael A. Batalia ◽  
Edward J. Collins
Keyword(s):  
Peptide Binding ◽  
Class Ii ◽  
Class I ◽  
Mhc Molecules ◽  
Class Ii Mhc

scholarly journals Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells

2007 ◽  
Vol 3 (4) ◽  
pp. 222-228 ◽  
Author(s):  
Prasanna Venkatraman ◽  
Tina T Nguyen ◽  
Matthieu Sainlos ◽  
Osman Bilsel ◽  
Sriram Chitta ◽  
...  
Keyword(s):  
Peptide Binding ◽  
Class Ii ◽  
Living Cells ◽  
Class Ii Mhc ◽  
Fluorogenic Probes

scholarly journals Regulation of antigen presentation by acidic pH.

1990 ◽  
Vol 171 (5) ◽  
pp. 1779-1784 ◽  
Author(s):  
P E Jensen
Keyword(s):  
T Cells ◽  
Complex Formation ◽  
Ph Dependence ◽  
Peptide Binding ◽  
Class Ii ◽  
Acidic Ph ◽  
Peptide Antigens ◽  
General Importance ◽  
Class Ii Mhc ◽  
Functional Peptide

The effect of pH on functional association of peptide antigens with APC membranes was investigated by using aldehyde-fixed B cells and class II-restricted T cell hybridomas to assess antigen/MHC complex formation. The results indicated that the rate and extent of functional peptide binding was markedly increased at pH 5.0 as compared with pH 7.3. The pH dependence of binding was preserved after pretreatment of fixed APC with pH 5.0 buffer, suggesting that pH had a direct effect on the interaction of peptide with the APC membrane. Similar results were obtained by using several peptides and I-Ad- and I-Ed-restricted T cells, indicating that pH may be of general importance in regulating the formation of functional antigen/class II MHC complexes.

Determination of Distinction Odortypes by Mutation of Class I and Class II MHC Genes

1990 ◽  
pp. 62-64 ◽  
Author(s):  
K. Yamazaki ◽  
G. K. Beauchamp ◽  
L. Thomas ◽  
J. Bard ◽  
E. A. Boyse
Keyword(s):  
Class Ii ◽  
Class I ◽  
Mhc Genes ◽  
Class Ii Mhc
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