scholarly journals Long-term repeatability of peripapillary optical coherence tomography angiography measurements in healthy eyes

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Woo Hyuk Lee ◽  
Min-Woo Lee ◽  
Min-Su Kim ◽  
Cheon Kuk Ryu ◽  
Jung-Yeul Kim
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Intraclass Correlation ◽  
Optical Coherence ◽  
Short Term ◽  
Factors Affecting ◽  
History Of ◽  
Short And Long Term ◽  
Healthy Eyes

AbstractThis is a prospective observational study to establish the short- and long-term repeatability of measurements of peripapillary optical coherence tomography angiography (OCTA) parameters in healthy eyes and identify factors affecting long-term repeatability. We enrolled 84 healthy eyes. Participants with a history of any ophthalmic disease (except high myopia) or intraocular surgery were excluded from the study. An experienced examiner performed OCTA using disc-centered 6 × 6 mm scans. All examinations were conducted twice at 5-min intervals at the initial visit and repeated at least 6 months later. For short-term repeatability, the coefficient of variation (CV) was 2.94–4.22% and the intraclass correlation coefficient (ICC) was 0.840–0.934. For long-term repeatability, the CV was 2.73–3.84% and the ICC was 0.737–0.934. Multivariate analyses showed that the axial length (AL) (B = 0.970; p = 0.002) and mean signal strength (SS) (B = − 2.028; p < 0.001) significantly affected long-term repeatability. Measurements of peripapillary OCTA parameters exhibited excellent short-term and good long-term repeatability in healthy individuals. The mean SS and AL affected long-term repeatability and should be considered while interpreting peripapillary OCTA images.

scholarly journals Repeatability of ocular surface vessel density measurements with optical coherence tomography angiography

2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Sijie Cai ◽  
Fengping Zhao ◽  
Chixin Du
Keyword(s):  
Optical Coherence Tomography ◽  
Ocular Surface ◽  
Optical Coherence Tomography Angiography ◽  
Imaging System ◽  
Intraclass Correlation ◽  
Vessel Density ◽  
Optical Coherence ◽  
Significant Difference ◽  
Surface Vessel ◽  
Healthy Eyes

Abstract Background To determine the repeatability of measurements of ocular surface vessel density in normal and diseased eyes using optical coherence tomography angiography (OCTA). Methods Ten normal eyes, 10 pinguecula eyes, and 10 pterygium eyes of 30 volunteers were subjected to OCTA (AngioVue Imaging System, Optovue, Inc.). For scanning, we used the corneal adapter module. Each eye was scanned three times in the nasal and temporal directions, separately. AngioVue software was used to generate the ocular surface vessel density. Ocular surface vessel density was defined as the proportion of vessel area with blood flow to the total measurement area (3 × 3 mm2). Intersession repeatability of the measurement was summarized as the coefficient of variation (CV), and intraclass correlation coefficients (ICC) were calculated by variance component models. Results The CVs were less than 5% in all subjects, and the ICCs exceeded 0.9; thus, all measurements showed good repeatability. The nasal vessels densities differed significantly between healthy eyes and eyes with pterygium (P < 0.05); however, there was no significant difference between healthy eyes and eyes with pinguecula (P = 0.466). Conclusions These results suggest that measurement of ocular surface vessel density by OCTA in normal eyes and eyes with pterygium and pinguecula is repeatable. This preliminary research describes a quantitative and visual method for assessing vessel density of the ocular surface with a high level of consistency.

scholarly journals Long‐term repeatability of optical coherence tomography angiography parameters in healthy eyes

2019 ◽  
Vol 98 (1) ◽  
Author(s):  
Min‐Woo Lee ◽  
Ki‐Yup Nam ◽  
Hyung‐Bin Lim ◽  
Hyung‐Moon Koo ◽  
Yong‐Il Shin ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Healthy Eyes

Long-term reproducibility of optical coherence tomography angiography in healthy and stable glaucomatous eyes

2021 ◽  
pp. bjophthalmol-2021-320034
Author(s):  
Takashi Nishida ◽  
Sasan Moghimi ◽  
Huiyuan Hou ◽  
James A Proudfoot ◽  
Aimee C Chang ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Open Angle Glaucoma ◽  
Intraclass Correlation ◽  
Capillary Density ◽  
Retinal Nerve Fibre Layer ◽  
Ganglion Cell Complex ◽  
Optical Coherence ◽  
Glaucoma Suspect

Background/aimsTo assess and compare long-term reproducibility of optic nerve head (ONH) and macula optical coherence tomography angiography (OCTA) vascular parameters and optical coherence tomography (OCT) thickness parameters in stable primary open-angle glaucoma (POAG), glaucoma suspect and healthy eyes.MethodsEighty-eight eyes (15 healthy, 38 glaucoma suspect and 35 non-progressing POAG) of 68 subjects who had at least three visits within 1–1.5 years with OCTA and OCT imaging (Angiovue; Optovue, Fremont, California, USA) on the same day were included. A series of vascular and thickness parameters were measured including macular parafoveal vessel density (pfVD), ONH circumpapillary capillary density (cpCD), macular parafoveal ganglion cell complex (pfGCC) and ONH circumpapillary retinal nerve fibre layer (cpRNFL). A random effects analysis of variance model was used to estimate intraclass correlation (ICC) coefficients and long-term variability estimates.ResultsICC was lower for OCTA (pfVD 0.823 (95% CI 0.736 to 0.888) and cpCD 0.871 (0.818 to 0.912)) compared with OCT (pfGCC 0.995 (0.993 to 0.997) and cpRNFL 0.975 (0.964 to 0.984)). Within-subject test–retest SD was 1.17% and 1.22% for pfVD and cpCD, and 0.57 and 1.22 µm for pfGCC and cpRNFL. Older age and lower signal strength index were associated with decreasing long-term variability of vessel densities.ConclusionsOCTA-measured macula and ONH vascular parameters have good long-term reproducibility, supporting the use of this instrument for longitudinal analysis. OCTA long-term reproducibility is less than OCT-measured thickness reproducibility. This needs to be taken into consideration when serial OCTA images are evaluated for change.Trial registration numberNCT00221897.

scholarly journals Evaluating Retinal and Choroidal Perfusion Changes After Ocular Massage of Healthy Eyes Using Optical Coherence Tomography Angiography

Medicina ◽  
2020 ◽  
Vol 56 (12) ◽  
pp. 645
Author(s):  
Felix Rommel ◽  
Sabine Lüken ◽  
Michelle Prasuhn ◽  
Maximilian Kurz ◽  
Vinodh Kakkassery ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Treatment Option ◽  
Optical Coherence Tomography Angiography ◽  
Retinal Artery Occlusion ◽  
Artery Occlusion ◽  
Optical Coherence ◽  
Capillary Plexus ◽  
Retinal Artery ◽  
The Impact ◽  
Healthy Eyes

Background and objectives: Ocular massage (OM) is used as a treatment option for acute retinal artery occlusion, under the assumption that it induces vessel dilatation and enhances perfusion. Since evidence of ocular perfusion alteration due to OM is lacking, we investigate the impact of OM on the hemodynamics of the posterior pole in healthy eyes in a noninvasive fashion by using optical coherence tomography angiography (OCTA). Materials and Methods: A prospective study was conducted on healthy volunteers, each of whom underwent measurements of intraocular pressure (IOP), central macular thickness (CMT), subfoveal choroidal thickness (SFCT), radial peripapillary capillary perfusion (RPCP), superficial capillary plexus perfusion (SCPP), deep capillary plexus perfusion (DCPP), choriocapillaris perfusion (CCP), Sattler’s layer perfusion (SLP) and Haller’s layer perfusion (HLP) before and after OM. OM was performed for 2 min, consisting of 10-s turns of compression and decompression of the globe. Results: A total of 21 eyes from 21 participants (median age 29) were included. After OM, IOP significantly declined (p < 0.001), while SFCT (p < 0.005), SCPP (p < 0.001), DCPP (p = 0.004) and CCP (p = 0.008) significantly increased. CMT, RPCP, SLP and HLP did not show any significant alteration due to OM. Changes in SCPP correlated positively with changes in CCP and vice versa. Conclusions: OCTA-based analysis in healthy adults following OM demonstrated a significant increase of retinal perfusion values, assumed to be due to failure of autoregulatory mechanisms. These findings may indicate a positive effect of OM as a treatment option for patients with acute retinal artery occlusion.

Ophthalmic Artery Occlusion From Injection of Heroin Into the Forehead

2019 ◽  
Vol 3 (4) ◽  
pp. 260-262
Author(s):  
Pimpiroon Ploysangam ◽  
Faruk Koreishi ◽  
Gareth M.C. Lema
Keyword(s):  
Optical Coherence Tomography ◽  
Ophthalmic Artery ◽  
Optical Coherence Tomography Angiography ◽  
Artery Occlusion ◽  
Severe Form ◽  
Optical Coherence ◽  
Retrospective Case ◽  
Retinal Hemorrhages ◽  
Disc Hemorrhage ◽  
History Of

Purpose: To report a case of ophthalmic artery occlusion after injection of heroin into the forehead. Methods: Retrospective case report. Results: A 27-year-old patient with a history of intravenous heroin abuse presented with a left ophthalmic artery occlusion after attempting to inject heroin into a vein in her forehead. Exam was significant for diffuse retinal edema, disc edema, disc hemorrhage, and diffuse retinal hemorrhages. Findings were also noted in the widefield image, optical coherence tomography, and optical coherence tomography angiography of the retina. Conclusions: This patient suffered from a severe form of talc retinopathy resulting in an ophthalmic artery occlusion after injecting heroin into her forehead. To our knowledge, this is the first instance of combined ophthalmic artery occlusion and talc retinopathy resulting from intentional injection into a superficial facial vein.

scholarly journals Comparison of Short- And Long-Term Variability in Standard Perimetry and Spectral Domain Optical Coherence Tomography in Glaucoma

2020 ◽  
Vol 210 ◽  
pp. 19-25 ◽  
Author(s):  
Carla N. Urata ◽  
Eduardo B. Mariottoni ◽  
Alessandro A. Jammal ◽  
Nara G. Ogata ◽  
Atalie C. Thompson ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Short And Long Term
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