scholarly journals Integrated intelligent computing application for effectiveness of Au nanoparticles coated over MWCNTs with velocity slip in curved channel peristaltic flow

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Muhammad Asif Zahoor Raja ◽  
Mohammad Sabati ◽  
Nabeela Parveen ◽  
Muhammad Awais ◽  
Saeed Ehsan Awan ◽  
...  

AbstractEstimation of the effectiveness of Au nanoparticles concentration in peristaltic flow through a curved channel by using a data driven stochastic numerical paradigm based on artificial neural network is presented in this study. In the modelling, nano composite is considered involving multi-walled carbon nanotubes coated with gold nanoparticles with different slip conditions. Modeled differential system of the physical problem is numerically analyzed for different scenarios to predict numerical data for velocity and temperature by Adams Bashforth method and these solutions are used as a reference dataset of the networks. Data is processed by segmentation into three categories i.e., training, validation and testing while Levenberg–Marquart training algorithm is adopted for optimization of networks results in terms of performance on mean square errors, train state plots, error histograms, regression analysis, time series responses, and auto-correlation, which establish the accurate and efficient recognition of trends of the system.

2019 ◽  
Vol 10 (5) ◽  
pp. 1521-1534 ◽  
Author(s):  
Imran Khan ◽  
Jinshen Lan ◽  
Mengyao Gao ◽  
Shengli Huang ◽  
Chenxu Wu

2011 ◽  
Vol 345 ◽  
pp. 381-386 ◽  
Author(s):  
Jian Guo Hou ◽  
Fu Tao Hu ◽  
Yu Ting Cao ◽  
Hai Juan Jin ◽  
Tian Hua Li ◽  
...  

A new method was established to construct a ultrasensitive electrochemiluminescence (ECL) immunosensor by using Ru@SiO2 (Ru(bpy)3 2+ doped silica) - doped Au (Ru@SiO2-Au) composite nanoparticles to label Ru-Ab2 (monoclonal α-fetoprotein (AFP) antibody labeled with Ru(bpy)32+). The primary antibody, anti-AFP was first immobilized on the multi-walled carbon nanotubes (MCNTs) modified with gold nanoparticles (MCNTs-Au) modified glassy carbon electrode due to the covalent conjugation, then the antigen and the Ru@SiO2-Au composite nanoparticles labeled Ru-Ab2 (Ru@SiO2-Au~Ru-Ab2)was conjugated successively to form a double-conjugated Ru(bpy)32+ sandwich-type immunocomplex through the specific interaction. Accordingly, through the ECL response of Ru@SiO2-Au~Ru-Ab2 and tripropylamine (TPA), a strong ECL signal was obtained and an amplification analysis of protein interaction was achieved. The present immunosensor performed high sensitivity and wide liner for detection α-fetoprotein (AFP) in the range of 0.05-80 ng mL−1 and the limit detection was 0.025 ng mL−1(defined as S/N=3). The morphologies of MCNTs, MCNTs-Au, Ru@SiO2 and Ru@SiO2-Au nanoparticles were characterized by using transmission electronic microscopy (TEM). The developed label and method is versatile, offers enhanced performances, and can be easily extended to other protein detection.


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