The CIP2A–TOPBP1 axis safeguards chromosome stability and is a synthetic lethal target for BRCA-mutated cancer

Nature Cancer ◽

10.1038/s43018-021-00266-w ◽

2021 ◽

Author(s):

Salomé Adam ◽

Silvia Emma Rossi ◽

Nathalie Moatti ◽

Mara De Marco Zompit ◽

Yibo Xue ◽

...

Keyword(s):

Chromosome Stability ◽

Synthetic Lethal

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SYNTHETIC LETHAL SCREENING OF ATP-LIKE PROTEIN INHIBITOR TO TERMINATE MITOSIS

European Journal of Biomedical and Life Sciences ◽

10.29013/elbls-20-2.3-51-58 ◽

2020 ◽

pp. 51-58

Author(s):

Z. Benran

Keyword(s):

Protein Inhibitor ◽

Synthetic Lethal

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Faculty Opinions recommendation of A conserved domain of Schizosaccharomyces pombe dfp1(+) is uniquely required for chromosome stability following alkylation damage during S phase.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1007257.91005 ◽

2002 ◽

Author(s):

Susan Forsburg

Keyword(s):

Schizosaccharomyces Pombe ◽

S Phase ◽

Chromosome Stability ◽

Alkylation Damage ◽

Conserved Domain

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Faculty Opinions recommendation of Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1104723.560791 ◽

2008 ◽

Author(s):

Michael Weber

Keyword(s):

Cancer Cells ◽

Synthetic Lethal ◽

Oncogenic Ras ◽

Nonapoptotic Cell Death

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Faculty Opinions recommendation of Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1162051.622560 ◽

2009 ◽

Author(s):

Junjie Chen

Keyword(s):

Cancer Cells ◽

Human Cancer ◽

Synthetic Lethal Interaction ◽

Synthetic Lethal ◽

Human Cancer Cells

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Faculty Opinions recommendation of Drosophila timeless2 is required for chromosome stability and circadian photoreception.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.2135956.2207055 ◽

2010 ◽

Author(s):

Steven Reppert

Keyword(s):

Chromosome Stability

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Faculty Opinions recommendation of Gene Essentiality Profiling Reveals Gene Networks and Synthetic Lethal Interactions with Oncogenic Ras.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727280568.793528542 ◽

2017 ◽

Author(s):

Eytan Ruppin ◽

Welles Robinson

Keyword(s):

Gene Networks ◽

Synthetic Lethal ◽

Gene Essentiality ◽

Oncogenic Ras ◽

Synthetic Lethal Interactions

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Faculty Opinions recommendation of Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727840921.793535557 ◽

2017 ◽

Author(s):

Michael Cole ◽

Elizabeth Sergison

Keyword(s):

Large Scale ◽

Synthetic Lethal ◽

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Chromosome Stability in Some Hexaploid Strains of Triticale 1

Crop Science ◽

10.2135/cropsci1969.0011183x000900020038x ◽

1969 ◽

Vol 9 (2) ◽

pp. 235-236 ◽

Author(s):

T. Tsuchiya ◽

E. N. Larter

Keyword(s):

Chromosome Stability

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Chromosome Stability and Fertility of a Nitrous Oxide‐Derived Tetraploid Population of Red Clover 1

Crop Science ◽

10.2135/cropsci1983.0011183x002300010013x ◽

1983 ◽

Vol 23 (1) ◽

pp. 45-48 ◽

Author(s):

N. Giri ◽

N. L. Taylor ◽

G. B. Collins

Keyword(s):

Nitrous Oxide ◽

Chromosome Stability ◽

Tetraploid Population

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Synthetic Lethal Interactions in Cancer Therapy

Current Cancer Drug Targets ◽

10.2174/1568009616666160426122736 ◽

2017 ◽

Vol 17 (4) ◽

pp. 304-310 ◽

Author(s):

Xinwei Geng ◽

Xiaohui Wang ◽

Dan Zhu ◽

Songmin Ying

Keyword(s):

Cancer Therapy ◽

Synthetic Lethal ◽

Synthetic Lethal Interactions

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