scholarly journals Letter commenting on ‘Survival after short- or long-term ventilation after acute spinal cord injury: a single-centre 25-year retrospective study’

Spinal Cord ◽  
2012 ◽  
Vol 50 (11) ◽  
pp. 859-860 ◽  
Author(s):  
J L Hutton ◽  
J H W Watt ◽  
E Wiredu
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Retrospective Study ◽  
Acute Spinal Cord Injury ◽  
Single Centre ◽  
Cord Injury ◽  
Long Term Ventilation

scholarly journals Role of methyleprednisolone succinate in the management of acute spinal cord injury

1970 ◽  
Vol 9 (3) ◽  
pp. 168-172
Author(s):  
NK Karn ◽  
BP Shrestha ◽  
GP Khanal ◽  
R Rijal ◽  
P Chaudhary ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Neurological Status ◽  
Acute Spinal Cord Injury ◽  
Cord Injury ◽  
And Gender ◽  
One Year

Objective: To see the role of methyleprednisolone succinate in the management of acute spinal cord injury. Methods: A randomized control trial was done including the patients with acute spinal cord injury. They were divided into age and gender matched two groups. Patients with presence of active infection, associated open fracture, those on long term steroid and those who did not give consent to participate in the trial were excluded. One group received methyleprednisolone succinate within 8 hours of injury and another group did not receive the drug. Both the groups were managed nonoperatively. The neurological status of the patients was assessed at presentation, once spinal shock was over, at 6th week and 6th month and after one year according to ASIA scoring. Frankel grading was also assessed in every follow up. Conclusion: Methylprednisolone succinct prevents secondary cord injury to a great extent and hence its administration within 8 hours of injury results in a better functional (motor and sensory) outcome. Keywords: acute spinal cord injury; methyleprednisolone succinate DOI: http://dx.doi.org/10.3126/hren.v9i3.5585   HR 2011; 9(3): 168-172

Early Administration of l-Arginine in Experimental Acute Spinal Cord Injury Impairs Long-Term Motor Function Recovery

2011 ◽  
Vol 70 (5) ◽  
pp. 1198-1202 ◽  
Author(s):  
Abdieel Esquivel-Aguilar ◽  
Gilberto Castañeda-Hernández ◽  
Angelina Martínez-Cruz ◽  
Rebecca E. Franco-Bourland ◽  
Ignacio Madrazo ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Motor Function ◽  
Acute Spinal Cord Injury ◽  
Early Administration ◽  
Function Recovery ◽  
Cord Injury

scholarly journals Serum cystatin C is increased in acute spinal cord injury: a multicentre retrospective study

Spinal Cord ◽  
2019 ◽  
Vol 58 (3) ◽  
pp. 341-347
Author(s):  
JinYuan Zhang ◽  
RuoTing Ding ◽  
QingZhang Xian ◽  
ZhiKun Wang ◽  
ZhongYuan Liu ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Retrospective Study ◽  
Cystatin C ◽  
Steroid Therapy ◽  
Acute Spinal Cord Injury ◽  
Serum Cystatin C ◽  
Serum Cystatin ◽  
Cord Injury ◽  
Multicentre Retrospective Study

Abstract Study design A multicentre retrospective study. Objective A multicentre retrospective study was performed to observe the changes in serum cystatin C (CysC) levels in patients with acute spinal cord injury (SCI). Setting Four hospitals in China. Methods Over a 5-year study period, the CysC, creatinine (Cr), and blood urea nitrogen (BUN) levels of people who had incurred SCI in the preceding 7 days were collected and compared with those of people with limb fracture (LF) who were matched for injury time and gender. People with SCI also were grouped by injury duration, ASIA Impairment Scale (AIS) grade and the presence or absence of steroid therapy and compared each day. Results Three hundred and twenty-three samples from people with SCI were retrospectively collected; their mean serum CysC levels were significantly higher than those of people with LF (p < 0.001); No significant difference was observed in Cr or BUN levels between the two groups (p > 0.14). CysC levels increased on the second day, peaked on day 3, and returned to normal on day 5. The more severely injured individuals had higher CysC levels. Steroid therapy or not had no influence for CysC levels. Conclusion CysC levels are increased in patients with acute SCI, possibly as a direct result of injury. Serum CysC is a potential biomarker of SCI.

scholarly journals Journal Club: Long-term functional outcome in patients with acquired infections after acute spinal cord injury

Neurology ◽  
2017 ◽  
Vol 89 (7) ◽  
pp. e76-e78 ◽  
Author(s):  
Freda M. Warner ◽  
Bobo Tong ◽  
Catherine R. Jutzeler ◽  
Jacquelyn J. Cragg ◽  
Paulina S. Scheuren ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Functional Outcome ◽  
Journal Club ◽  
Acute Spinal Cord Injury ◽  
Cord Injury
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