scholarly journals Translational utility of rodent hippocampal auditory gating in schizophrenia research: a review and evaluation

2015 ◽  
Vol 5 (6) ◽  
pp. e587-e587 ◽  
Author(s):  
J Smucny ◽  
K E Stevens ◽  
A Olincy ◽  
J R Tregellas
Keyword(s):  
Auditory Gating

Auditory Gating and Extended High-Frequency Thresholds in Normal-Hearing Adults With Minimal Tinnitus

2019 ◽  
Vol 28 (1S) ◽  
pp. 209-224 ◽  
Author(s):  
Julia Campbell ◽  
Alison LaBrec ◽  
Connor Bean ◽  
Mashhood Nielsen ◽  
Won So
Keyword(s):  
High Frequency ◽  
Normal Hearing ◽  
Auditory Gating

scholarly journals The Inferior Colliculus in Alcoholism and Beyond

2020 ◽  
Vol 14 ◽  
Author(s):  
Tanuja Bordia ◽  
Natalie M. Zahr
Keyword(s):  
Inferior Colliculus ◽  
Ethanol Exposure ◽  
Ethanol Withdrawal ◽  
Hypoxic Injury ◽  
Auditory Gating ◽  
Korsakoff Syndrome ◽  
Altered Metabolism ◽  
Magnetic Resonance Imaging Mri ◽  
Inferior Colliculi

Post-mortem neuropathological and in vivo neuroimaging methods have demonstrated the vulnerability of the inferior colliculus to the sequelae of thiamine deficiency as occurs in Wernicke-Korsakoff Syndrome (WKS). A rich literature in animal models ranging from mice to monkeys—including our neuroimaging studies in rats—has shown involvement of the inferior colliculi in the neural response to thiamine depletion, frequently accomplished with pyrithiamine, an inhibitor of thiamine metabolism. In uncomplicated alcoholism (i.e., absent diagnosable neurological concomitants), the literature citing involvement of the inferior colliculus is scarce, has nearly all been accomplished in preclinical models, and is predominately discussed in the context of ethanol withdrawal. Our recent work using novel, voxel-based analysis of structural Magnetic Resonance Imaging (MRI) has demonstrated significant, persistent shrinkage of the inferior colliculus using acute and chronic ethanol exposure paradigms in two strains of rats. We speculate that these consistent findings should be considered from the perspective of the inferior colliculi having a relatively high CNS metabolic rate. As such, they are especially vulnerable to hypoxic injury and may be provide a common anatomical link among a variety of disparate insults. An argument will be made that the inferior colliculi have functions, possibly related to auditory gating, necessary for awareness of the external environment. Multimodal imaging including diffusion methods to provide more accurate in vivo visualization and quantification of the inferior colliculi may clarify the roles of brain stem nuclei such as the inferior colliculi in alcoholism and other neuropathologies marked by altered metabolism.

Improved P50 Auditory Gating With Ondansetron in Medicated Schizophrenia Patients

2005 ◽  
Vol 162 (2) ◽  
pp. 386-388 ◽  
Author(s):  
Lawrence E. Adler ◽  
Ellen M. Cawthra ◽  
Kara A. Donovan ◽  
Josette G. Harris ◽  
Herbert T. Nagamoto ◽  
...  
Keyword(s):  
Auditory Gating

Auditory gating processes and binaural inhibition in the inferior colliculus

2002 ◽  
Vol 168 (1-2) ◽  
pp. 98-109 ◽  
Author(s):  
Liang Li ◽  
Qi Yue
Keyword(s):  
Inferior Colliculus ◽  
Auditory Gating

Scalp recordings of mid-latency AEP and auditory gating in the Göttingen minipig: a new animal model in information processing research

2004 ◽  
Vol 52 (3) ◽  
pp. 267-275 ◽  
Author(s):  
S.M Arnfred ◽  
N.M Lind ◽  
A Gjedde ◽  
A.K Hansen
Keyword(s):  
Animal Model ◽  
Information Processing ◽  
Göttingen Minipig ◽  
Auditory Gating

Hippocampal auditory gating in the hyperactive mocha mouse

1999 ◽  
Vol 276 (1) ◽  
pp. 57-60 ◽  
Author(s):  
Christine L Miller ◽  
Margit Burmeister ◽  
Karen E Stevens
Keyword(s):  
Auditory Gating

Rats Reared in Social Isolation Show Schizophrenia-Like Changes in Auditory Gating

1997 ◽  
Vol 58 (4) ◽  
pp. 1031-1036 ◽  
Author(s):  
Karen E Stevens ◽  
Robert G Johnson ◽  
Gregory M Rose
Keyword(s):  
Social Isolation ◽  
Auditory Gating

scholarly journals Long-term potentiation disrupts auditory gating in the rat hippocampus

1995 ◽  
Vol 15 (8) ◽  
pp. 5820-5830 ◽  
Author(s):  
CL Miller ◽  
PC Bickford ◽  
AK Wiser ◽  
GM Rose
Keyword(s):  
Long Term Potentiation ◽  
Rat Hippocampus ◽  
Auditory Gating ◽  
Term Potentiation

ICV injections of antisense oligonucleotides for the α7 nicotinic receptor reduce auditory gating in sprague-Dawley rats

2003 ◽  
Vol 60 (1) ◽  
pp. 261
Author(s):  
K. Stevens ◽  
H.C. O'Neill ◽  
M.P. Schmitt ◽  
K. Rieger ◽  
J.K. Smith ◽  
...  
Keyword(s):  
Antisense Oligonucleotides ◽  
Nicotinic Receptor ◽  
Sprague Dawley ◽  
Auditory Gating ◽  
Sprague Dawley Rats

Alpha-MSH and MCH are functional antagonists in a CNS auditory gating paradigm

Peptides ◽  
1993 ◽  
Vol 14 (3) ◽  
pp. 431-440 ◽  
Author(s):  
Christine L. Miller ◽  
Victor J. Hruby ◽  
Terry O. Matsunaga ◽  
Paula C. Bickford
Keyword(s):  
Auditory Gating ◽  
Gating Paradigm
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