Chapter 8. Elucidating Biomolecular Structure Through Bond-selective Radical Fragmentation

2020 ◽  
pp. 195-208
Author(s):  
Evan E. Hubbard ◽  
Ryan R. Julian
Keyword(s):  
Biomolecular Structure ◽  
Radical Fragmentation

scholarly journals Promiscuous molecules for smarter file operations in DNA-based data storage

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Kyle J. Tomek ◽  
Kevin Volkel ◽  
Elaine W. Indermaur ◽  
James M. Tuck ◽  
Albert J. Keung
Keyword(s):  
Data Storage ◽  
Data Access ◽  
Molecular Architecture ◽  
Biomolecular Structure ◽  
Jpeg Images ◽  
Storage Media ◽  
Dna Storage ◽  
Dna Strands ◽  
Background Database ◽  
Organizational Features

AbstractDNA holds significant promise as a data storage medium due to its density, longevity, and resource and energy conservation. These advantages arise from the inherent biomolecular structure of DNA which differentiates it from conventional storage media. The unique molecular architecture of DNA storage also prompts important discussions on how data should be organized, accessed, and manipulated and what practical functionalities may be possible. Here we leverage thermodynamic tuning of biomolecular interactions to implement useful data access and organizational features. Specific sets of environmental conditions including distinct DNA concentrations and temperatures were screened for their ability to switchably access either all DNA strands encoding full image files from a GB-sized background database or subsets of those strands encoding low resolution, File Preview, versions. We demonstrate File Preview with four JPEG images and provide an argument for the substantial and practical economic benefit of this generalizable strategy to organize data.

scholarly journals Geometric Deep Learning on Biomolecular Structure

2021 ◽  
Vol 120 (3) ◽  
pp. 290a
Author(s):  
Raphael Townshend ◽  
Ligia Melo ◽  
David Liu ◽  
Ron O. Dror
Keyword(s):  
Deep Learning ◽  
Biomolecular Structure

Amplified Vibrational Circular Dichroism as a Probe of Local Biomolecular Structure

2014 ◽  
Vol 136 (9) ◽  
pp. 3530-3535 ◽  
Author(s):  
Sérgio R. Domingos ◽  
Adriana Huerta-Viga ◽  
Lambert Baij ◽  
Saeed Amirjalayer ◽  
Dorien A. E. Dunnebier ◽  
...  
Keyword(s):  
Circular Dichroism ◽  
Vibrational Circular Dichroism ◽  
Biomolecular Structure ◽  
Circular Dichroïsm

scholarly journals Toolkit for Multi-Conformation Biomolecular Structure Determination by High-Precision FRET and Molecular Simulations

2015 ◽  
Vol 108 (2) ◽  
pp. 163a-164a
Author(s):  
Mykola Dimura ◽  
Stanislav Kalinin ◽  
Thomas Peulen ◽  
Holger Gohlke ◽  
Claus A.M. Seidel
Keyword(s):  
High Precision ◽  
Structure Determination ◽  
Molecular Simulations ◽  
Biomolecular Structure

scholarly journals Molecular Insights into Biomolecular Structure and Dynamics by 14 N NMR

2017 ◽  
Vol 112 (3) ◽  
pp. 447a
Author(s):  
Maria Concistre ◽  
James A. Jarvis ◽  
Ibraheem M. Haies ◽  
Ilya Kuprov ◽  
Marina Carravetta ◽  
...  
Keyword(s):  
Biomolecular Structure ◽  
Structure And Dynamics
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