Chapter 15. Identification of α7 Nicotinic Acetylcholine Receptor Agonists for their Assessment in Improving Cognition in Schizophrenia

Nicotinic Acetylcholine ◽

Alpha7 nicotinic acetylcholine receptor agonists and PAMs as adjunctive treatment in schizophrenia. An experimental study

European Neuropsychopharmacology ◽

10.1016/j.euroneuro.2016.07.004 ◽

2016 ◽

Vol 26 (9) ◽

pp. 1401-1411 ◽

Cited By ~ 14

Author(s):

Monica M. Marcus ◽

Carl Björkholm ◽

Anna Malmerfelt ◽

Annie Möller ◽

Ninni Påhlsson ◽

...

Keyword(s):

Experimental Study ◽

Acetylcholine Receptor ◽

Adjunctive Treatment ◽

Nicotinic Acetylcholine ◽

Alpha7 Nicotinic Acetylcholine Receptor ◽

Selective α7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis

British Journal of Pharmacology ◽

10.1111/j.1476-5381.2010.00699.x ◽

2010 ◽

Vol 160 (2) ◽

pp. 322-333 ◽

Cited By ~ 58

Author(s):

Susanne A Snoek ◽

Marleen I Verstege ◽

Esmerij P van der Zanden ◽

Nigel Deeks ◽

David C Bulmer ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Experimental Colitis ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

3 α7 Nicotinic Acetylcholine Receptor Agonists and Positive Allosteric Modulators

Progress in Medicinal Chemistry - Progress in Medicinal Chemistry Volume 46 ◽

10.1016/s0079-6468(07)00003-3 ◽

2008 ◽

pp. 131-171 ◽

Cited By ~ 31

Author(s):

Andrew P. Lightfoot ◽

James N.C. Kew ◽

John Skidmore

Keyword(s):

Acetylcholine Receptor ◽

Allosteric Modulators ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Receptor Agonists ◽

Positive Allosteric Modulators

Process Optimization for the Large-Scale Preparation of (2S,3aR,7aS)-tert-Butyl Hexahydro-2,5-methanopyrrolo[3,2-c]pyridine-1(4H)-carboxylate, an Intermediate for Nicotinic Acetylcholine Receptor Agonists

Organic Process Research & Development ◽

10.1021/acs.oprd.8b00208 ◽

2018 ◽

Vol 22 (9) ◽

pp. 1276-1281 ◽

Cited By ~ 2

Author(s):

Lokesh Babu Jarugu ◽

China Anki Reddy ◽

Nanjundaswamy Kanikahalli Chikkananjunda ◽

Suresh Krishnamoorthy ◽

Pon Sarvanakumar ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Process Optimization ◽

Large Scale ◽

Nicotinic Acetylcholine ◽

Tert Butyl ◽

Receptor Agonists ◽

Large Scale Preparation ◽

Scale Preparation

Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: Correlation with desensitization of α4β2* receptors

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2012.09.014 ◽

2012 ◽

Vol 47 (5) ◽

pp. 813-823 ◽

Cited By ~ 14

Author(s):

Jiahui Zhang ◽

Yun-De Xiao ◽

Kristen G. Jordan ◽

Phil S. Hammond ◽

Katherine M. Van Dyke ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Receptor Agonists ◽

Analgesic Effects

P.689 Cognitive enhancers in schizophrenia: A meta-analysis of Alpha-7 nicotinic acetylcholine receptor agonists for cognitive deficits and negative symptoms

European Neuropsychopharmacology ◽

10.1016/j.euroneuro.2019.09.657 ◽

2019 ◽

Vol 29 ◽

pp. S465-S466

Author(s):

M. Recio-Barbero ◽

A. Zabala ◽

R. Segarra ◽

B. Santos ◽

F.J. Ballesteros

Keyword(s):

Acetylcholine Receptor ◽

Cognitive Deficits ◽

Negative Symptoms ◽

Meta Analysis ◽

Nicotinic Acetylcholine ◽

Cognitive Enhancers ◽

Receptor Agonists ◽

Alpha 7

Neurobiological Impact of Nicotinic Acetylcholine Receptor Agonists: An Activation Likelihood Estimation Meta-Analysis of Pharmacologic Neuroimaging Studies

Biological Psychiatry ◽

10.1016/j.biopsych.2014.12.021 ◽

2015 ◽

Vol 78 (10) ◽

pp. 711-720 ◽

Cited By ~ 30

Author(s):

Matthew T. Sutherland ◽

Kimberly L. Ray ◽

Michael C. Riedel ◽

Julio A. Yanes ◽

Elliot A. Stein ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Meta Analysis ◽

Likelihood Estimation ◽

Activation Likelihood Estimation ◽

Nicotinic Acetylcholine ◽

Differential antagonism and tolerance/cross-tolerance among nicotinic acetylcholine receptor agonists

Behavioural Pharmacology ◽

10.1097/fbp.0000000000000233 ◽

2016 ◽

Vol 27 ◽

pp. 240-248 ◽

Cited By ~ 7

Author(s):

Fernando B. de Moura ◽

Lance R. McMahon

Keyword(s):

Acetylcholine Receptor ◽

Cross Tolerance ◽

Nicotinic Acetylcholine ◽

Design of novel α7-subtype-preferring nicotinic acetylcholine receptor agonists: Application of docking and MM-PBSA computational approaches, synthetic and pharmacological studies

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.09.073 ◽

2009 ◽

Vol 19 (22) ◽

pp. 6353-6357 ◽

Cited By ~ 24

Author(s):

Giovanni Grazioso ◽

Diego Yuri Pomè ◽

Carlo Matera ◽

Fabio Frigerio ◽

Luca Pucci ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Computational Approaches ◽

Receptor Agonists ◽

Pharmacological Studies

Effects of α7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis

Psychopharmacology ◽

10.1007/s00213-011-2535-6 ◽

2011 ◽

Vol 220 (4) ◽

pp. 823-833 ◽

Cited By ~ 13

Author(s):

Kathy L. Kohlhaas ◽

Robert S. Bitner ◽

Murali Gopalakrishnan ◽

Lynne E. Rueter

Keyword(s):

Mouse Model ◽

Acetylcholine Receptor ◽

Α7 Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Receptor Agonists ◽

Antipsychotic Efficacy