Effects of α7 nicotinic acetylcholine receptor agonists on antipsychotic efficacy in a preclinical mouse model of psychosis

Nicotinic Acetylcholine ◽

Receptor Agonists ◽

Antipsychotic Efficacy

Pharmacological modulation of the α7 nicotinic acetylcholine receptor in a mouse model of mecamylamine-precipitated nicotine withdrawal

Psychopharmacology ◽

10.1007/s00213-018-4879-7 ◽

2018 ◽

Vol 235 (7) ◽

pp. 1897-1905 ◽

Cited By ~ 10

Author(s):

Asti Jackson ◽

Roger L. Papke ◽

M. Imad Damaj

Keyword(s):

Mouse Model ◽

Acetylcholine Receptor ◽

Nicotine Withdrawal ◽

Nicotinic Acetylcholine ◽

Pharmacological Modulation

Selective α7 nicotinic acetylcholine receptor agonists worsen disease in experimental colitis

British Journal of Pharmacology ◽

10.1111/j.1476-5381.2010.00699.x ◽

2010 ◽

Vol 160 (2) ◽

pp. 322-333 ◽

Cited By ~ 58

Author(s):

Susanne A Snoek ◽

Marleen I Verstege ◽

Esmerij P van der Zanden ◽

Nigel Deeks ◽

David C Bulmer ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Experimental Colitis ◽

Nicotinic Acetylcholine ◽

Receptor Agonists

3 α7 Nicotinic Acetylcholine Receptor Agonists and Positive Allosteric Modulators

Progress in Medicinal Chemistry - Progress in Medicinal Chemistry Volume 46 ◽

10.1016/s0079-6468(07)00003-3 ◽

2008 ◽

pp. 131-171 ◽

Cited By ~ 31

Author(s):

Andrew P. Lightfoot ◽

James N.C. Kew ◽

John Skidmore

Keyword(s):

Acetylcholine Receptor ◽

Allosteric Modulators ◽

Nicotinic Acetylcholine ◽

Receptor Agonists ◽

Positive Allosteric Modulators

α7 nicotinic acetylcholine receptor-mediated neuroprotection against dopaminergic neuron loss in an MPTP mouse model via inhibition of astrocyte activation

Journal of Neuroinflammation ◽

10.1186/1742-2094-9-98 ◽

2012 ◽

Vol 9 (1) ◽

Cited By ~ 56

Author(s):

Yuan Liu ◽

Jun Hu ◽

Jie Wu ◽

Chenlei Zhu ◽

Yujian Hui ◽

...

Keyword(s):

Mouse Model ◽

Acetylcholine Receptor ◽

Dopaminergic Neuron ◽

Astrocyte Activation ◽

Nicotinic Acetylcholine ◽

Neuron Loss ◽

Dopaminergic Neuron Loss

Reducing inflammation and rescuing FTD-related behavioral deficits in progranulin-deficient mice with α7 nicotinic acetylcholine receptor agonists

Biochemical Pharmacology ◽

10.1016/j.bcp.2015.07.016 ◽

2015 ◽

Vol 97 (4) ◽

pp. 454-462 ◽

Cited By ~ 11

Author(s):

S. Sakura Minami ◽

Vivian Shen ◽

David Le ◽

Grietje Krabbe ◽

Rustam Asgarov ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Behavioral Deficits ◽

Nicotinic Acetylcholine ◽

Receptor Agonists ◽

Deficient Mice

α7 nicotinic acetylcholine receptor-specific stimulation ameliorates cognitive impairment in a mouse model of Alzheimer's disease via suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis

Proceedings for Annual Meeting of The Japanese Pharmacological Society ◽

10.1254/jpssuppl.wcp2018.0_or4-4 ◽

2018 ◽

Vol WCP2018 (0) ◽

pp. OR4-4

Author(s):

Kazuyuki Takata ◽

Shohei Kawanishi ◽

Eriko Kuroda ◽

Shigehiko Takegami ◽

Tatsuya Kitade ◽

...

Keyword(s):

Cognitive Impairment ◽

Mouse Model ◽

Acetylcholine Receptor ◽

Amyloid Β ◽

Nicotinic Acetylcholine ◽

Model Of Alzheimer’S Disease ◽

Secretase Activity ◽

Specific Stimulation

Therapeutic potential of α7 nicotinic acetylcholine receptor agonists to combat obesity, diabetes, and inflammation

Reviews in Endocrine and Metabolic Disorders ◽

10.1007/s11154-020-09584-3 ◽

2020 ◽

Vol 21 (4) ◽

pp. 431-447

Author(s):

Han Xie ◽

Natesh Yepuri ◽

Qinghe Meng ◽

Ravi Dhawan ◽

Colin A. Leech ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Therapeutic Potential ◽

Nicotinic Acetylcholine ◽

Receptor Agonists

Synthesis and SAR studies of 1,4-diazabicyclo[3.2.2]nonane phenyl carbamates – subtype selective, high affinity α7 nicotinic acetylcholine receptor agonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.06.059 ◽

2009 ◽

Vol 19 (16) ◽

pp. 4747-4751 ◽

Cited By ~ 10

Author(s):

Christopher J. O’Donnell ◽

Langu Peng ◽

Brian T. O’Neill ◽

Eric P. Arnold ◽

Robert J. Mather ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Receptor Agonists ◽

High Affinity ◽

Sar Studies ◽

Subtype Selective

In Vivo Evaluation of α7 Nicotinic Acetylcholine Receptor Agonists [11C]A-582941 and [11C]A-844606 in Mice and Conscious Monkeys

PLoS ONE ◽

10.1371/journal.pone.0008961 ◽

2010 ◽

Vol 5 (2) ◽

pp. e8961 ◽

Cited By ~ 23

Author(s):

Jun Toyohara ◽

Kiichi Ishiwata ◽

Muneyuki Sakata ◽

Jin Wu ◽

Shingo Nishiyama ◽

...

Keyword(s):

Acetylcholine Receptor ◽

In Vivo Evaluation ◽

Nicotinic Acetylcholine ◽

Receptor Agonists

Gamma-lactams—A novel scaffold for highly potent and selective α7 nicotinic acetylcholine receptor agonists

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2009.01.073 ◽

2009 ◽

Vol 19 (5) ◽

pp. 1287-1291 ◽

Cited By ~ 20

Author(s):

Albert Enz ◽

Dominik Feuerbach ◽

Mathias U. Frederiksen ◽

Conrad Gentsch ◽

Konstanze Hurth ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Receptor Agonists ◽

Novel Scaffold