Drug Discovery for Psychiatric Disorders

2012 ◽  
Keyword(s):  
Drug Discovery ◽  
Psychiatric Disorders

scholarly journals Redesigning antidepressant drug discovery

2014 ◽  
Vol 16 (1) ◽  
pp. 5-7
Keyword(s):  
Drug Discovery ◽  
Animal Models ◽  
Psychiatric Disorders ◽  
Antidepressant Drug ◽  
Diagnostic Process ◽  
Pharmaceutical Companies ◽  
Drug Discovery And Development ◽  
Drug Candidates ◽  
Rapid Transfer ◽  
Efficacy Studies

Antidepressant drug discovery and development have been put on hold by many pharmaceutical companies. The main reason for this is the negative efficacy studies with novel specific drugs. Here I argue that the main obstacles are the absence of gene tests and biomarkers as an integral part of a diagnostic process. Further, too much emphasis has been put on validating drug candidates in animal models of psychiatric disorders. A more rapid transfer of drug candidates into human research is necessary to overcome current obstacles that prevent the discovery of next-generation antidepressants.

scholarly journals Calcium Imaging in Drug Discovery for Psychiatric Disorders

2020 ◽  
Vol 11 ◽  
Author(s):  
Saurav Seshadri ◽  
Daniel J. Hoeppner ◽  
Katsunori Tajinda
Keyword(s):  
Drug Discovery ◽  
Psychiatric Disorders ◽  
Calcium Imaging

5-HT Receptor-Associated Protein Networks: New Targets for Drug Discovery in Psychiatric Disorders?

2012 ◽  
Vol 13 (1) ◽  
pp. 28-52 ◽  
Author(s):  
Philippe Marin ◽  
Carine Becamel ◽  
Aline Dumuis ◽  
Joel Bockaert
Keyword(s):  
Drug Discovery ◽  
Psychiatric Disorders ◽  
Protein Networks ◽  
Receptor Associated Protein ◽  
New Targets

Primate-Accelerated Evolutionary Genes: Novel Routes to Drug Discovery in Psychiatric Disorders

2010 ◽  
Vol 17 (13) ◽  
pp. 1300-1316 ◽  
Author(s):  
J. Moalic ◽  
Y. Le Strat ◽  
A. Lepagnol-Bestel ◽  
N. Ramoz ◽  
Y. Loe-Mie ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Psychiatric Disorders
Sign in / Sign up

Export Citation Format

Share Document