Supramolecular catalysis of H/D exchange in pyruvate by macrocyclic polyamines involving a reactive iminium intermediate

1997 ◽  
pp. 2073-2081 ◽  
Author(s):  
Hicham Fenniri ◽  
Carol Dallaire ◽  
Daniel P. Funeriu ◽  
Jean-Marie Lehn
Keyword(s):  
Supramolecular Catalysis ◽  
Macrocyclic Polyamines

Supramolecular Catalysis of H/D Exchange in Malonate Ions by Macrocyclic Polyamines: A Model Enzyme with Enolase Activity

1996 ◽  
Vol 35 (3) ◽  
pp. 337-339 ◽  
Author(s):  
Hicham Fenniri ◽  
Jean-Marie Lehn ◽  
Annie Marquis-Rigault
Keyword(s):  
Supramolecular Catalysis ◽  
Macrocyclic Polyamines

ChemInform Abstract: Supramolecular Catalysis in the Hydrolysis of ATP Facilitated by Macrocyclic Polyamines: Mechanistic Studies.

ChemInform ◽  
1987 ◽  
Vol 18 (22) ◽  
Author(s):  
M. W. HOSSEINI ◽  
J.-M. LEHN ◽  
L. MAGGIORA ◽  
K. B. MERTES ◽  
M. P. MERTES
Keyword(s):  
Mechanistic Studies ◽  
Supramolecular Catalysis ◽  
Macrocyclic Polyamines ◽  
Hydrolysis Of

Supramolecular catalysis in the hydrolysis of ATP facilitated by macrocyclic polyamines: mechanistic studies

1987 ◽  
Vol 109 (2) ◽  
pp. 537-544 ◽  
Author(s):  
Mir Wais Hosseini ◽  
Jean Marie Lehn ◽  
Linda Maggiora ◽  
Kristin B. Mertes ◽  
Mathias P. Mertes
Keyword(s):  
Mechanistic Studies ◽  
Supramolecular Catalysis ◽  
Macrocyclic Polyamines ◽  
Hydrolysis Of

Role of Functionalized Pillararene Architectures in Supramolecular Catalysis

2020 ◽  
Author(s):  
Kaiya Wang ◽  
Jacobs H. Jordan ◽  
Krishnasamy Velmurugan ◽  
Xueqi Tian ◽  
Minzan Zuo ◽  
...  
Keyword(s):  
Supramolecular Catalysis

Developments in functionalization of macrocyclic polyamines

1989 ◽  
Vol 61 (5) ◽  
pp. 823-828 ◽  
Author(s):  
E. Kimura
Keyword(s):  
Macrocyclic Polyamines

Synthesis of a Macrobicyclic Thiazolium-Host and Supramolecular Catalysis of the Benzoin Condensation

1986 ◽  
Vol 25 (12) ◽  
pp. 1125-1127 ◽  
Author(s):  
Heinz-Dieter Lutter ◽  
Fran�ois Diederich
Keyword(s):  
Supramolecular Catalysis ◽  
Benzoin Condensation

Effective and reversible DNA condensation induced by bifunctional molecules containing macrocyclic polyamines and naphthyl moieties

2012 ◽  
Vol 20 (2) ◽  
pp. 801-808 ◽  
Author(s):  
Hao Yan ◽  
Zhi-Fen Li ◽  
Zhi-Fo Guo ◽  
Zhong-Lin Lu ◽  
Feng Wang ◽  
...  
Keyword(s):  
Dna Condensation ◽  
Bifunctional Molecules ◽  
Macrocyclic Polyamines

Dimeric Macrocyclic Polyamines with Potent Inhibitory Activity against Human Immunodeficiency Virus

1995 ◽  
Vol 6 (5) ◽  
pp. 337-344 ◽  
Author(s):  
Y. Inouye ◽  
T. Kanamori ◽  
M. Sugiyama ◽  
T. Yoshida ◽  
T. Koike ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Cytopathic Effect ◽  
Syncytium Formation ◽  
Physiological Conditions ◽  
Structure Activity ◽  
Immunodeficiency Virus ◽  
Macrocyclic Polyamines ◽  
Anti Hiv ◽  
Viral Cytopathic Effect ◽  
Potent Inhibitory Activity

The structure-activity relationships of monomeric and dimeric macrocyclic polyamines were studied in an attempt to find potent inhibitors of human immunodeficiency virus (HIV) types 1 and 2. In general, dimeric polyamines are superior as HIV inhibitors to their monomeric counterparts, and the activity of a dimer is proportional to that of its constituent monomers. For the monomeric compounds, the amount of positive charge on the monomer rings under physiological conditions was more important for anti-HIV activity than the ring size. On the basis of these findings, the 14-membered tetraamine cyclam was selected as the component of dimeric compounds with potentially high activity. Of the series of newly synthesized bicyclams, in which the monomeric cyclams were linked at each C-6 position, a compound with an aIkyI chain bridge three carbons in length was found to exhibit the maximum anti-HIV activity. For one particular strain (HIV-2GH-1), syncytium formation was inhibited by the bicyclams at a similar concentration to that required to inhibit the viral cytopathic effect.

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