Nanopatterning molecularly imprinted polymers by soft lithography: a hierarchical approach

Lab on a Chip ◽  
2010 ◽  
Vol 10 (10) ◽  
pp. 1316 ◽  
Author(s):  
Hélène Lalo ◽  
Cédric Ayela ◽  
Etienne Dague ◽  
Christophe Vieu ◽  
Karsten Haupt
2007 ◽  
Vol 1004 ◽  
Author(s):  
Kyung Choi

AbstractWe demonstrate functional microfabrications generated using photocurable functional polymers. We synthesized photocurable silicon elastomers, which can be useful for high fidelity, nano-scale soft lithography. ‘Elastic photopatterns’ generated by using the designed photocuarble silicon elastomers was presented. Molecularly imprinted polymers (MIP) are produced by “molecular imprinting technique”, which is a general protocol for the preparation of “synthetic receptor sites”. We then used the MIP's system for functional pattern fabrications to improve the sensitivity of molecular recognitions. Those functional microfabrications are beneficial to develop actual devices with high performances.


2002 ◽  
Vol 723 ◽  
Author(s):  
Jennifer J. Brazier ◽  
Mingdi Yan ◽  
Scott Prahl ◽  
Yin-Chu Chen

AbstractThis article demonstrates the novel approach of fabricating molecularly imprinted polymers (MIPs) as fiber optic waveguides for the detection of fluorescent analytes. Combining a polyurethane system and the soft lithography technique of micromolding in capillaries (MIMIC), polymer waveguides of 50 νm and 100 νm dimensions were patterned onto a silicon substrate. Laser coupling into small waveguide segments has been verified visually. Binding experiments using the waveguides are currently being explored. Some preliminary binding studies have been performed, however, for smaller, freestanding filaments of sizes consistent with conventionally prepared MIP particles. Using fluorimetry measurements, templated fibers of 20 νm dimension preferentially bound the analyte molecules by a factor of 1.5 as compared to control polymers.


2011 ◽  
Vol 1218 (14) ◽  
pp. 1828-1834 ◽  
Author(s):  
Claudio Baggiani ◽  
Patrizia Baravalle ◽  
Cristina Giovannoli ◽  
Laura Anfossi ◽  
Cinzia Passini ◽  
...  

2010 ◽  
Vol 38 (3) ◽  
pp. 401-404
Author(s):  
Da-Wei LOU ◽  
Ying-Jie YANG ◽  
Guang HUANG ◽  
Ping-Li PU ◽  
Xin-Qing LEE ◽  
...  

2019 ◽  
Vol 31 (11) ◽  
pp. 2527-2531
Author(s):  
St. Fauziah ◽  
N.H. Soekamto ◽  
P. Budi ◽  
P. Taba

Molecularly imprinted polymers (MIP) as an adsorbent has been synthesized using β-sitosterol as molecule template on free radical polymerization reaction. The capacity and selectivity of the adsorption from MIP to β-sitosterol was studied in this study. The β-sitosterol concentration in the adsorption-desorption test and the MIP selectivity test were analyzed by UV-visible and HPLC. The MIP obtained from the synthesis results in a high adsorption capacity. Based on the Freundlich adsorption isothermal equation, the adsorption capacity (k) was found to be 1.24 mg/g. The MIP can adsorb 100 % β-sitosterol while cholesterol was only 3 %. The MIP is most selective to β-sitosterol, therefore, has high potential to apply as adsorbent at solid phase extraction method to isolate β-sitosterol from sample extract.


Author(s):  
P. U. Ashvin Iresh Fernando ◽  
Matthew W. Glasscott ◽  
Kaytee Pokrzywinski ◽  
Brianna M. Fernando ◽  
Gilbert K. Kosgei ◽  
...  

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