Lab on a Chip
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Published By The Royal Society Of Chemistry

1473-0189, 1473-0197
Updated Wednesday, 19 January 2022

Lab on a Chip ◽  
2022 ◽  
Author(s):  
Miyuki Sakuma ◽  
Xiao Wang ◽  
Felix Ellett ◽  
Jon F. Edd ◽  
Babatunde Kehinde ◽  
...  

Neutrophils are the largest population of white blood cells in the circulation, and their primary function is to protect the body from microbes. They can release the chromatin in their...


Lab on a Chip ◽  
2022 ◽  
Author(s):  
Logan M. Wilder ◽  
Jonathan R. Thompson ◽  
Richard M. Crooks

The pH of droplets moving through a microchannel is regulated in real time by water electrolysis. Resulting droplet pHs are within ±0.1 pH units of the predicted values.


Lab on a Chip ◽  
2022 ◽  
Author(s):  
Yoshikazu Kameda ◽  
Surachada Chuaychob ◽  
Miwa Tanaka ◽  
Yang Liu ◽  
Ryu Okada ◽  
...  

Three-dimensional (3D) tissue culture is a powerful tool for understanding physiological events. However, 3D tissues still have limitations in their size, culture period, and maturity, which are caused by the...


Lab on a Chip ◽  
2022 ◽  
Author(s):  
Koji Yamashita ◽  
Hirohito Sawahata ◽  
Shota Yamagiwa ◽  
Shohei Yokoyama ◽  
Rika Numano ◽  
...  

Microelectrode technology is essential in electrophysiology and has made contributions to neuroscience as well as to medical applications. However, it is necessary to minimize tissue damage associated with needle-like electrode...


Lab on a Chip ◽  
2022 ◽  
Author(s):  
Nan Xiang ◽  
Zhonghua Ni

On-chip concentration of rare malignant tumor cells (MTCs) in malignant pleural effusions (MPEs) with a large volume is challenging. Previous microfluidic concentrators suffer from a low concentration factor (CF) and...


Lab on a Chip ◽  
2022 ◽  
Author(s):  
Roozbeh Abedini-Nassab ◽  
Xianting Ding ◽  
Haiyang Xie

The use of magnetic micro- and nanoparticles in medicine and biology is expanding. One important example is the transport of magnetic microparticles and magnetized cells in lab-on-a-chip systems. The magnetic...


Lab on a Chip ◽  
2022 ◽  
Author(s):  
Lin Sun ◽  
Thomas Lehnert ◽  
Songjing Li ◽  
Martin A. M. Gijs

We present a new bubble-enhanced microfluidic approach for highly efficient DNA fragmentation, suitable for next generation sequencing platforms. Improved on-chip performance arises from acoustic streaming generated by oscillating bubble interfaces.


Lab on a Chip ◽  
2022 ◽  
Author(s):  
Beatrise Berzina ◽  
Sungu Kim ◽  
Umesha Peramune ◽  
Kumar Saurabh ◽  
Baskar Ganapathysubramanian ◽  
...  

Ion concentration polarization (ICP) accomplishes preconcentration for bioanalysis by localized depletion of electrolyte ions, thereby generating a gradient in electric field strength that facilitates electrokinetic focusing of charged analytes by...


Lab on a Chip ◽  
2022 ◽  
Author(s):  
Amir Mokhtare ◽  
Benyamin Davaji ◽  
Philip Xie ◽  
Mohammad Yaghoobi ◽  
Zev Rosenwaks ◽  
...  

Cumulus removal (CR) is a central prerequisite step for many protocols involved in the assisted reproductive technology (ART) such as intracytoplasmic sperm injection (ICSI) and preimplantation genetic testing (PGT). The...


Lab on a Chip ◽  
2022 ◽  
Author(s):  
Hui Li ◽  
Pengfei Zhang ◽  
Kuangwen Hsieh ◽  
Tza-Huei Wang
Keyword(s):  

We have developed a combinatorial nanodroplet platform for screening antibiotic combinations and successfully screened drug response of pairwise antibiotic combinations from selected antibiotics using the platform.


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