Modular synthesis of optically active lactones by Ru-catalyzed asymmetric allylic carboxylation and ring-closing metathesis reaction

2012 ◽  
Vol 48 (32) ◽  
pp. 3872 ◽  
Author(s):  
Koichiro Takii ◽  
Naoya Kanbayashi ◽  
Kiyotaka Onitsuka
Keyword(s):  
Optically Active ◽  
Metathesis Reaction ◽  
Ring Closing Metathesis ◽  
Modular Synthesis

Stereoselective synthesis of optically active dihydrofurans and dihydropyrans via a ring closing metathesis reaction

2011 ◽  
Vol 22 (11) ◽  
pp. 1161-1168 ◽  
Author(s):  
Merve Çayir ◽  
Sema Demirci ◽  
Serdar Sezer ◽  
Cihangir Tanyeli
Keyword(s):  
Stereoselective Synthesis ◽  
Optically Active ◽  
Metathesis Reaction ◽  
Ring Closing Metathesis

Synthesis of Pyrrolo[1,2-a][1,6]- and [1,8]naphthyridines by Alkyne-Carbonyl Metathesis

Synthesis ◽  
2020 ◽  
Author(s):  
Peter Ehlers ◽  
Peter Langer ◽  
Marian Blanco Ponce ◽  
Silvio Parpart ◽  
Alexander Villinger ◽  
...  
Keyword(s):  
Heterocyclic Compounds ◽  
Metathesis Reaction ◽  
Synthetic Methodology ◽  
Facile Synthesis ◽  
Reaction Conditions ◽  
One Pot ◽  
Metal Free ◽  
Modular Synthesis

AbstractA concise and modular synthesis of pyrrolo[1,2-a][1,6]- and [1,8]naphthyridines by a one-pot two-step reaction consisting of electrophilic acylation followed by an alkyne-carbonyl-metathesis reaction as the final cyclization step is reported. This developed synthetic methodology allows the facile synthesis of these heterocyclic core structures in mainly high overall yields under metal-free conditions. Reaction conditions are carefully optimized and display a novel supplement to access these tricyclic heterocyclic compounds.

Modular Synthesis of Optically Active Tröger’s Base Analogues

ChemPlusChem ◽  
2013 ◽  
Vol 78 (12) ◽  
pp. 1510-1516 ◽  
Author(s):  
Takuya Kamiyama ◽  
Merve Sinem Özer ◽  
Elisabeth Otth ◽  
Jan Deska ◽  
Ján Cvengroš
Keyword(s):  
Optically Active ◽  
Modular Synthesis ◽  
Troger's Base

A Double Ring Closing Metathesis Reaction in the Rapid, Enantioselective Synthesis of NK-1 Receptor Antagonists

2001 ◽  
Vol 3 (5) ◽  
pp. 671-674 ◽  
Author(s):  
Debra J. Wallace ◽  
Jonathan M. Goodman ◽  
Derek J. Kennedy ◽  
Antony J. Davies ◽  
Cameron J. Cowden ◽  
...  
Keyword(s):  
Enantioselective Synthesis ◽  
Metathesis Reaction ◽  
Receptor Antagonists ◽  
Ring Closing Metathesis ◽  
Double Ring

Synthesis of New Tricyclic Spirobispidines via Ring Closing Metathesis Reaction

Heterocycles ◽  
2007 ◽  
Vol 71 (11) ◽  
pp. 2331 ◽  
Author(s):  
Christian Hametner ◽  
Daniel Dangl ◽  
Kurt Mereiter ◽  
Martina Marchetti ◽  
Johannes Fröhlich
Keyword(s):  
Metathesis Reaction ◽  
Ring Closing Metathesis

Progress Towards the Stereoselective Synthesis of 3,6-Disubstituted 1,2-Diamino-4-cyclohexenes by Ring Closing Metathesis Reaction.

ChemInform ◽  
2003 ◽  
Vol 34 (15) ◽  
Author(s):  
Stefano Grilli ◽  
Gianluca Martelli ◽  
Diego Savoia ◽  
Carla Zazzetta
Keyword(s):  
Stereoselective Synthesis ◽  
Metathesis Reaction ◽  
Ring Closing Metathesis

scholarly journals Synthesis of fluorinated δ-lactams via cycloisomerization of gem-difluoropropargyl amides

2010 ◽  
Vol 6 ◽  
Author(s):  
Satoru Arimitsu ◽  
Gerald B Hammond
Keyword(s):  
Building Blocks ◽  
Alder Reaction ◽  
Diels Alder ◽  
Tandem Reaction ◽  
Enyne Metathesis ◽  
Metathesis Reaction ◽  
Ring Closing Metathesis ◽  
Diels Alder Reaction

gem-Difluoro-1,7-enyne amides are suitable building blocks for the synthesis of difluorodihydropyridinones via a ring-closing metathesis reaction, and of 4,4-difluoro-3-oxoisoquinolines through a ring-closing metathesis–enyne metathesis tandem reaction. These products, in turn, undergo a Diels–Alder reaction to yield heterotricyclic systems in moderate to good yields.

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